REducing the Risk of COgnitive DEcline ad Dementia in Patients With Subjective Cognitive Decline Through an Immersive Virtual Reality and Telemedicine-based Multi-component Intervention: the SCD-ReCODED Study

NARecruitingINTERVENTIONAL
Enrollment

75

Participants

Timeline

Start Date

July 1, 2024

Primary Completion Date

May 31, 2025

Study Completion Date

December 31, 2025

Conditions
Subjective Cognitive Decline
Interventions
DEVICE

Multi-component Intervention (MC-I): VR Cognitive training and Psychoeducation on health and lifestyle

"In a period of 5 consecutive weeks, participants will receive:~* an interactive immersive virtual reality cognitive training for 30 minutes, 3 days per week. It consists in different tasks implemented in virtual real-like scenarios of daily living situations that target the following cognitive processes: long-term associative memory, relational binding, spatial pattern separation and pattern completion;~* an interactive immersive virtual reality health and lifestyle education program for 30 minutes, 1 day per week. It consists in 360° videos aimed at advancing awareness and knowledge of the various health conditions associated with an increased risk of cognitive decline and dementia and helping participants to develop a healthier lifestyle."

DEVICE

Cognitive-only intervention (CO-I): VR Cognitive training (+ Psychoeducation active control)

"In a period of 5 consecutive weeks, participants will receive:~* the interactive immersive virtual reality cognitive training as described in the MC-I condition, for about 30 minutes, 3 days per week;~* an active control of the immersive virtual reality psychoeducation program for 30 minutes, 1 day per week."

DEVICE

Active control intervention (AC-I): VR Cognitive active control + Psychoeducation active control

"In a period of 5 consecutive weeks, participants will receive:~* an active control of the immersive virtual reality cognitive training (participants will be requested to virtually carry out daily actions, in the same setting as those performed in cognitive immersive VR training, but they will follow prearranged instructions requiring very low cognitive demands) for about 30 minutes, 3 days per week;~* an active control of the immersive virtual reality psychoeducation program for about 30 minutes, 1 day per week."

Trial Locations (1)

00179

RECRUITING

I.R.C.C.S Santa Lucia Foundation, Rome

All Listed Sponsors
lead

I.R.C.C.S. Fondazione Santa Lucia

OTHER