Chitosan-Hyaluronate Gel Mixture Vs Hyaluronic for Internal Derangement

PHASE4RecruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

January 17, 2024

Primary Completion Date

June 1, 2024

Study Completion Date

July 1, 2024

Conditions
TMJ Disc Disorder
Interventions
DRUG

Chitosan-Hyaluronate Gel Mixture

The operation will be under GA. TMJ arthroscopy will performed by the same TMJ arthroscopy surgeon. Lysis and lavage will be performed in the upper joint space in all cases based on the triangulation technique with an inferolateral approach. The arthroscopic procedure will include lysis of adhesions, lavage, manipulation, and debridement of the upper joint space. A 1.9-mm arthroscope with a video monitoring and recording system and a 2.2-mm protective cannula sheath will be used for TMJ arthroscopy. Ringer's lactate will be used as irrigation fluid. Both groups will receive the same arthroscopic treatments. The injection of 2 ml of Chitosan-Hyaluronate Gel Mixture into affected joints will be performed. Needles will be removed after the injection sites and covered its sites with gauze dressing.

DRUG

Hyaluronic Acid

The operation will be under GA. TMJ arthroscopy will performed by the same TMJ arthroscopy surgeon. Lysis and lavage will be performed in the upper joint space in all cases based on the triangulation technique with an inferolateral approach. The arthroscopic procedure will include lysis of adhesions, lavage, manipulation, and debridement of the upper joint space. A 1.9-mm arthroscope with a video monitoring and recording system and a 2.2-mm protective cannula sheath will be used for TMJ arthroscopy. Ringer's lactate will be used as irrigation fluid. Both groups will receive the same arthroscopic treatments. The injection of 2 ml of Hyaluronic acid into affected joints will be performed. Needles will be removed after the injection sites and covered its sites with gauze dressing.

Trial Locations (1)

41522

RECRUITING

Suez University, Suez

All Listed Sponsors
collaborator

Misr International University

OTHER

collaborator

University of Nizwa

UNKNOWN

lead

Ain Shams University

OTHER