Insulin and Insulin Pulses During Fasting

NARecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

September 15, 2024

Primary Completion Date

September 1, 2026

Study Completion Date

September 1, 2027

Conditions
PreDiabetes
Interventions
OTHER

Intralipid and heparin

Intralipid (20%, 0.011ml/kg/min; Baxter, Healthcare, Deerfield, IL) and heparin (200 units prime, 0.2 unit/kg/min continuous) will be infused to induce acute insulin resistance

OTHER

Saline

Saline will be infused

Trial Locations (1)

55905

RECRUITING

Mayo Clinic in Rochester, Rochester

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Mayo Clinic

OTHER