Effect of Pentoxifylline Versus Probiotic on Preterm Neonates With Necrotizing Enterocolitis

PHASE3CompletedINTERVENTIONAL
Enrollment

75

Participants

Timeline

Start Date

June 30, 2022

Primary Completion Date

November 1, 2023

Study Completion Date

December 30, 2023

Conditions
Necrotizing Enterocolitis
Interventions
DRUG

Pentoxifylline

Pentoxifylline 30 mg/kg given over 6 hours daily

DRUG

Probiotic Formula

probiotics sachets supplementation, in the form of lyophilized lactic acid bacteria each Aluminium stick pack contains 100 mg ( Meyer et al., 2020) Probio Tec BB12-Blend 30- IF\* (SANDOZ®.) mixed with 10 ml sterile water and given by Ryle tube once daily until discharge from the unit after clinical and laboratory improvement .

Trial Locations (1)

Unknown

Tanta University, Tanta

All Listed Sponsors
lead

Tanta University

OTHER