Variations in the Hemostatic System Induced by a Standardized Walking Test

Treadmill walking test in the morning, 2 hours after breakfast, following a clinical examination, resting 12-lead electrocardiogram and blood pressure measurement. After a 3-minute warm-up and walking of speed 2.5 km per hour, no incline, the speed and incline are gradually increased to reach a target heart rate close to the theoretical ventilatory threshold, around 70% of the theoretical maximum value (evaluated by Astrand's formula: 220-age), i.e. aerobic conditions of moderate intensity so that prolonged effort can be maintained. Test performed in presence of a physician trained in stress testing. Emergency cart and defibrillator available in the department. Intra-hospital vital emergency protocol in place, with resuscitation teams on standby. The cardiology department, in the same building, can be contacted in the event of a cardiological abnormality during the test or recovery. The test takes 60 minutes, including a 3-minute initial warm-up.

33.3 ml of blood will be taken from each participant whilst at rest, before undergoing the 60-minute walking test

33.3 ml of blood will be taken from each participant immediately after undergoing the 60-minute walking test.

An electrocardiogram will be carried out throughout the exercise period and during the first 30 minutes of recovery.

Blood pressure will be monitored out throughout the exercise period and during the first 30 minutes of recovery.