Short-course Radiotherapy or Long-course Chemoradiation Followed by MFOLFOXIRI Consolidation Chemotherapy for Organ Preservation in Low Rectal Cancer

The total dosage was 25Gy consisted of 5 fractions of 5 Gy to clinical target volume without a boost dose

150 mg/m² iv drip over 2 hours on day 1, repeated every 14 days.

85 mg/m² iv drip over 2 hours on day 1, repeated every 14 days.

400 mg/m² iv drip over 2 hours on day 1, repeated every 14 days.

2400 mg/m² iv drip over 48 hours on day 1-2, repeated every 14 days.

The total dosage was 50Gy consisted of 25 fractions of 2 Gy to clinical target volume without a boost dose

825 mg/m² twice daily administered orally and concurrently with radiation therapy for 5 days per week.