Exercise Training and Rehabilitation In Cardiac Amyloidosis

NAEnrolling by invitationINTERVENTIONAL
Enrollment

34

Participants

Timeline

Start Date

January 10, 2024

Primary Completion Date

January 30, 2024

Study Completion Date

June 30, 2026

Conditions
Cardiac Amyloidosis
Interventions
OTHER

Exercise training (ET1+ET2)

Exercise training will consist of continuous aerobic training of moderate intensity on cycle ergometer/treadmill, with a frequency of 2-3 weekly sessions lasting 12 weeks, with exercise intensity of VO2 peak of 40% gradually increasing up to 50-60% of VO2 peak based on individual tolerability and improvement; 55-65% of heart rate at peak; 40-59% of heart rate reserve; 4-6 Metabolic equivalents (METS); the duration of the session will gradually increase from 15-30 min to 45-60 min.

BEHAVIORAL

Optimal Medical Therapy (No-ET)

Patients will be handled according to optimal medical therapy

Trial Locations (1)

80131

Department of Translational Medical Sciences, Naples

All Listed Sponsors
lead

Federico II University

OTHER