Dexmeditomedine as an Adjuvant to Levobupivacaine in Transversus Thoracis Plane Block on the Management of Post-sternotomy Pain in Open-heart Surgeries

NANot yet recruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

June 15, 2024

Primary Completion Date

June 15, 2025

Study Completion Date

July 15, 2025

Conditions
Pain, Postoperative
Interventions
PROCEDURE

transversus thoracis plane block

with the patient lying in the supine position. After skin disinfection, a high frequency linear ultrasound probe will be applied parallel to and between the 4th and 5th ribs connecting at the sternum. Then, different drugs according to the different groups will be injected between the transversus thoracic muscle and the internal intercosatal muscle.

DRUG

Dexmedetomidine

the dexmeditomedine group shall undergo bilateral transversus thoracis plane block with 15 ml of 25% levobupivacaine, and 0.05 ug/kg dexmeditomedine on each side of the sternum

DRUG

Levobupivacaine

A local anesthetic that will be instilled in the transversus thoracic plane in a dose of 15 ml of a 25% concentration on both sides of the sternum in both groups

All Listed Sponsors
lead

Assiut University

OTHER

NCT06410404 - Dexmeditomedine as an Adjuvant to Levobupivacaine in Transversus Thoracis Plane Block on the Management of Post-sternotomy Pain in Open-heart Surgeries | Biotech Hunter | Biotech Hunter