Impact of Topical Pentoxifylline and Tocopherol in Treatment and Prevention of Medically-related Osteonecrosis of the Jaws

NACompletedINTERVENTIONAL
Enrollment

48

Participants

Timeline

Start Date

April 2, 2020

Primary Completion Date

December 17, 2023

Study Completion Date

January 24, 2024

Conditions
Medically Related Osteonecrosis of the Jaws
Interventions
DRUG

Tocopherol and pentoxifilline topical gel

Oral gel applied locally on the MRONJ related lesions or post-extraction sockets

DRUG

Placebo

Oral gel applied locally on the MRONJ related lesions or post-extraction sockets

Trial Locations (1)

95124

AOU Policlinico G. Rodolico, Catania

All Listed Sponsors
lead

University of Catania

OTHER

NCT06409546 - Impact of Topical Pentoxifylline and Tocopherol in Treatment and Prevention of Medically-related Osteonecrosis of the Jaws | Biotech Hunter | Biotech Hunter