Neoantigen Vaccine Plus Capecitabine as Adjuvant Therapy for Intrahepatic Cholangiocarcinoma After Radical Resection

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

May 6, 2024

Primary Completion Date

May 31, 2026

Study Completion Date

May 31, 2026

Conditions
Intrahepatic Cholangiocarcinoma
Interventions
COMBINATION_PRODUCT

Neoantigen Vaccine plus Capecitabine

"1. Capecitabine.Twice a day, 30 minutes after breakfast, swallow with water, continue for 2 weeks, then stop for 1 week, constitutes one cycle; three weeks make one cycle, lasting for 8 cycles.~2. Neoantigen Vaccine . Every 3 weeks, once every 21 days, for 4 to 8 cycles. The injection is administered on the first day after cessation of capecitabine. Treatment can last for up to 6 months without occurrences such as the researcher determining no further clinical benefit, intolerable toxic reactions, initiation of new anti-tumor treatment, withdrawal of informed consent, loss to follow-up, death, or other circumstances specified in the protocol that require treatment termination."

Trial Locations (1)

Unknown

RECRUITING

Mengchao Hepatobiliary Hospital, Fujian Medical University, Fuzhou

All Listed Sponsors
lead

Yongyi Zeng

OTHER