Diode Laser Photo Activation for Pocket Reduction Decontamination A Clinical Study

PHASE1CompletedINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

May 28, 2023

Primary Completion Date

August 1, 2023

Study Completion Date

September 15, 2023

Conditions
Pocket, PeriodontalPeriodontal InflammationPeriodontal Attachment LossPeriodontitis
Interventions
COMBINATION_PRODUCT

Diode laser and 3% hydrogen peroxide

"Hydrogen peroxide due to its super radicals has a local antimicrobial effect. Since hydrogen peroxide can be easily available in a clinical setting and is cost-effective. It could be used for photo disinfection along with lasers.~The diode lasers that belong to the 655-980 nm spectrum could represent a safer alternative. Because of the transmission or scattering effect on hydroxyapatite, diode lasers have no effect on hard tissues and deposits. The photoactivation procedure uses photolysis of hydrogen peroxide with 810nm laser.~Hydrogen peroxide acts as an endogenous dye, which can increase the laser effect at this level and also generate ROS. Thus the combination of 3% H2O2 and laser light generate hydroxyl radicals as a result of photoactivation.~Therefore, the diode laser stimulation of 3%hydrogen peroxide has been utilized adjunctive to SRP to optimize clinical outcomes."

Trial Locations (1)

562157

Anusha s, Bengaluru

All Listed Sponsors
lead

Krishnadevaraya College of Dental Sciences & Hospital

OTHER

NCT06404190 - Diode Laser Photo Activation for Pocket Reduction Decontamination A Clinical Study | Biotech Hunter | Biotech Hunter