RECOVER-ENERGIZE Platform Protocol

NARecruitingINTERVENTIONAL
Enrollment

660

Participants

Timeline

Start Date

July 17, 2024

Primary Completion Date

July 31, 2026

Study Completion Date

July 31, 2026

Conditions
Long COVIDLong Covid19Long Covid-19
Interventions
BEHAVIORAL

Personalized Cardiopulmonary Rehabilitation

"Participants in this group will complete 2-3 cardiopulmonary rehabilitation sessions per week, for 12 weeks, as tolerated. Rehabilitation sessions are provided by respiratory therapists, exercise physiologists, physical therapists, nurses, or others who have experience and training in either pulmonary or cardiac rehabilitation.~Rehabilitation sessions (adjusted based on the participant's baseline assessment, symptoms, and progress) last about 1 hour and include education, aerobic exercise, strength, and flexibility training."

BEHAVIORAL

Structured Pacing

Participants in this group will complete weekly pacing sessions for 12 weeks. Pacing sessions will last about 30 minutes, as tolerated. Each participant will meet with a provider 'pacing coach' who has received study-specific education about PEM and how to create and manage pacing strategies for participants. Sessions include PEM symptom and trigger assessment; task, function and activity analysis; adaptations and modifications.

OTHER

Education

Participants in this group will receive two general education sessions at the start of the intervention with weekly phone/virtual follow-ups from site study staff.

OTHER

Usual Care

Participants in this group will receive basic education about PEM with a weekly call by site study staff for support and communication.

Trial Locations (42)

11220

RECRUITING

NYU Langone Health/Brooklyn Hospital, Brooklyn

15213

RECRUITING

University of Pittsburgh, Pittsburgh

25701

RECRUITING

University Physicians and Surgeons, Inc dba Marshall Health, Huntington

26506

RECRUITING

West Virginia Clinical and Translational Science Institute, Morgantown

27514

RECRUITING

University of North Carolina Hospital, Chapel Hill

27710

RECRUITING

Duke University Medical Center, Durham

30030

RECRUITING

Emory Hope Clinic, Decatur

30303

RECRUITING

Grady Memorial Hospital (Emory), Atlanta

32209

RECRUITING

University of Florida College of Medicine Jacksonville, Jacksonville

33144

RECRUITING

Innovation Clinical Trials Inc., Miami

33165

RECRUITING

Valencia Medical and Research Center, Miami

35205

RECRUITING

University of Alabama at Birmingham, Birmingham

40536

RECRUITING

University of Kentucky, Lexington

48202

RECRUITING

Henry Ford Hospital, Detroit

50701

RECRUITING

Cedar Valley Clinical Research, Waterloo

55905

RECRUITING

Mayo Clinic, Rochester

57108

RECRUITING

Avera McKennan Hospital & University Health Center, Sioux Falls

60201

RECRUITING

North Shore University HealthSystem/Evanston Hospital, Evanston

60608

RECRUITING

University of Illinois at Chicago, Chicago

60612

RECRUITING

Rush University Medical Center, Chicago

61637

RECRUITING

Saint Francis Medical Center, Peoria

63110

RECRUITING

Washington University School of Medicine, St Louis

66160

RECRUITING

Kansas University Medical Center, Kansas City

75235

RECRUITING

Southwest Family Medicine Associates, Dallas

77030

RECRUITING

Houston Methodist Hospital, Houston

RECRUITING

University of Texas Health Science Center at Houston, Houston

80045

RECRUITING

University of Colorado, Aurora

84132

RECRUITING

University of Utah, Salt Lake City

85006

RECRUITING

Banner University Medical Center Phoenix, Phoenix

85719

RECRUITING

Banner University Medical Center Tucson, Tucson

87102

RECRUITING

University of New Mexico Health Sciences Center, Albuquerque

90509

RECRUITING

Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance

94035

RECRUITING

Stanford University, Stanford

06520-8017

RECRUITING

Yale - New Haven Hospital, New Haven

04074

RECRUITING

Maine Health Institute of Research, Scarborough

02111

RECRUITING

Tufts Medical Center, Boston

02114

RECRUITING

Massachusetts General Hospital, Boston

02115

RECRUITING

Brigham and Women's Hospital, Boston

02215

RECRUITING

Beth Israel Deaconess Med. Ctr., Boston

03756

RECRUITING

Dartmouth Hitchcock Medical Center, Lebanon

97239-3098

RECRUITING

Oregon Health and Science University, Portland

05446

RECRUITING

Vermont Lung Center, University of Vermont, Colchester

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

lead

Duke University

OTHER