The Influence of Oxytocin on Intrapartum Fetal Well-being and Delivery Outcomes in Patients Receiving Epidural Analgesia

NAEnrolling by invitationINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

May 6, 2024

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Uterine ContractionOxytocinLabor ProgressFetal DopplerLabor Epidural AnalgesiaLabor Pain
Interventions
OTHER

Continuation of oxytocin after ELA

"The use of oxytocin will be continued after the administration of ELA. The vital signs (blood pressure, saturation, heart rate) and the Doppler velocities in the uterine arteries, umbilical artery and the fetal middle cerebral artery will be measured directly before the administration of ELA and then after 30, 60 and 120 minutes. After 2 hours the patients will be examined to assess the progress of labor.~Additionally, the velocities in the uterine arteries will be measured during the first day after the delivery."

OTHER

Discontinuation of oxytocin after ELA

The oxytocin pump will be changed to 0.9% sodium chloride solution pump after the administration of ELA. The vital signs (blood pressure, saturation, heart rate) and the Doppler velocities in the uterine arteries, umbilical artery and the fetal middle cerebral artery will be measured directly before the administration of ELA and then after 30, 60 and 120 minutes. After 2 hours the patients will be examined to assess the progress of labor. If no progress is detected due to the secondary weakening of uterus contractile function, the oxytocin will be reintroduced. Additionally, the velocities in the uterine arteries will be measured during the first day after the delivery.

Trial Locations (1)

02-507

Clinical Department of Obstetrics and Perinatology, National Medical Institute of the Ministry of the Interior and Administration, Warsaw

All Listed Sponsors
collaborator

Medical University of Warsaw

OTHER

lead

Central Clinical Hospital of the Ministry of Internal Affairs and Administration, Warsaw, Poland

OTHER