Selected Lysosomal Enzyme Activities and the Oxidant-antioxidant Balance in Hyperbaric Oxygen Condition.

NACompletedINTERVENTIONAL
Enrollment

78

Participants

Timeline

Start Date

April 26, 2016

Primary Completion Date

December 31, 2020

Study Completion Date

December 31, 2020

Conditions
Hyperbaric OxygenationOxygen ToxicityAntioxidantsOxidative Stress
Interventions
PROCEDURE

Hyperbaric Oxygen Therapy

HBO session includes three 20-minute inhalations of pure oxygen in a hyperbaric chamber utilizing specially fitted face masks for each patient. The session is conducted as follows: 10 minutes compression of up to 2.5 atm (0.25 MPa), inhalation of 100% oxygen for 20 minutes, a 5-minute break in the chamber without the mask (oxygen concentration up to 23%, constant temperature (room) and humidity), again 20 minutes inhalation of 100% oxygen, another 5-minute break (the same condition), the last 20 minutes inhalation of 100% oxygen, and finally a 10-minute decompression. The total duration of the session was 90 minutes.

Trial Locations (1)

85-092

Department of Medical Biology and Biochemistry, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Karlowicza 24, 85-092 Bydgoszcz, Poland, Bydgoszcz

All Listed Sponsors
lead

Nicolaus Copernicus University

OTHER

NCT06401941 - Selected Lysosomal Enzyme Activities and the Oxidant-antioxidant Balance in Hyperbaric Oxygen Condition. | Biotech Hunter | Biotech Hunter