1,656
Participants
Start Date
April 15, 2025
Primary Completion Date
February 13, 2031
Study Completion Date
February 13, 2031
Bone Scan
Undergo bone scan for patients with metastatic sites outside the chest/abdomen/pelvis documented during therapy
Carboplatin
Given IV
Computed Tomography
Undergo CT
Cyclophosphamide
Given IV
Dactinomycin
Given IV
Doxorubicin
Given IV
Etoposide
Given IV
Irinotecan
Given IV
Magnetic Resonance Imaging
Undergo MRI
Nephrectomy
Undergo nephrectomy
Patient Observation
Undergo observation after nephrectomy
Positron Emission Tomography
Undergo PET for patients with metastatic sites outside the chest/abdomen/pelvis documented during therapy
Ultrasound Imaging
Undergo ultrasound
Vincristine
Given IV
X-Ray Imaging
Undergo X-ray
RECRUITING
New York Medical College, Valhalla
RECRUITING
NYU Langone Hospital - Long Island, Mineola
RECRUITING
Stony Brook University Medical Center, Stony Brook
RECRUITING
Albany Medical Center, Albany
RECRUITING
State University of New York Upstate Medical University, Syracuse
RECRUITING
Roswell Park Cancer Institute, Buffalo
RECRUITING
Children's Hospital of Pittsburgh of UPMC, Pittsburgh
RECRUITING
Penn State Children's Hospital, Hershey
RECRUITING
Geisinger Medical Center, Danville
RECRUITING
Children's Hospital of Philadelphia, Philadelphia
RECRUITING
Alfred I duPont Hospital for Children, Wilmington
RECRUITING
Children's National Medical Center, Washington D.C.
RECRUITING
University of Maryland/Greenebaum Cancer Center, Baltimore
RECRUITING
Sinai Hospital of Baltimore, Baltimore
RECRUITING
Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore
RECRUITING
University of Virginia Cancer Center, Charlottesville
RECRUITING
VCU Massey Comprehensive Cancer Center, Richmond
RECRUITING
Children's Hospital of The King's Daughters, Norfolk
RECRUITING
Carilion Children's, Roanoke
RECRUITING
Duke University Medical Center, Durham
RECRUITING
East Carolina University, Greenville
RECRUITING
Prisma Health Richland Hospital, Columbia
RECRUITING
BI-LO Charities Children's Cancer Center, Greenville
RECRUITING
Children's Healthcare of Atlanta - Arthur M Blank Hospital, Atlanta
RECRUITING
Nemours Children's Clinic-Jacksonville, Jacksonville
RECRUITING
Nemours Children's Clinic - Pensacola, Pensacola
RECRUITING
Arnold Palmer Hospital for Children, Orlando
RECRUITING
Nemours Children's Hospital, Orlando
RECRUITING
Memorial Regional Hospital/Joe DiMaggio Children's Hospital, Hollywood
RECRUITING
Broward Health Medical Center, Fort Lauderdale
RECRUITING
Saint Mary's Medical Center, West Palm Beach
RECRUITING
Children's Hospital of Alabama, Birmingham
RECRUITING
Vanderbilt University/Ingram Cancer Center, Nashville
RECRUITING
East Tennessee Childrens Hospital, Knoxville
NOT_YET_RECRUITING
Saint Jude Children's Research Hospital, Memphis
RECRUITING
University of Mississippi Medical Center, Jackson
RECRUITING
University of Kentucky/Markey Cancer Center, Lexington
RECRUITING
ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital, Toledo
RECRUITING
Children's Hospital Medical Center of Akron, Akron
RECRUITING
Cincinnati Children's Hospital Medical Center, Cincinnati
RECRUITING
Dayton Children's Hospital, Dayton
RECRUITING
Riley Hospital for Children, Indianapolis
RECRUITING
C S Mott Children's Hospital, Ann Arbor
RECRUITING
Children's Hospital of Michigan, Detroit
RECRUITING
Bronson Methodist Hospital, Kalamazoo
RECRUITING
University of Iowa/Holden Comprehensive Cancer Center, Iowa City
RECRUITING
Saint Vincent Hospital Cancer Center Green Bay, Green Bay
RECRUITING
University of Minnesota/Masonic Cancer Center, Minneapolis
RECRUITING
Mayo Clinic in Rochester, Rochester
RECRUITING
Lurie Children's Hospital-Chicago, Chicago
RECRUITING
University of Chicago Comprehensive Cancer Center, Chicago
RECRUITING
Saint Jude Midwest Affiliate, Peoria
RECRUITING
Cardinal Glennon Children's Medical Center, St Louis
RECRUITING
Washington University School of Medicine, St Louis
RECRUITING
Children's Mercy Hospitals and Clinics, Kansas City
RECRUITING
Children's Hospital and Medical Center of Omaha, Omaha
RECRUITING
University of Nebraska Medical Center, Omaha
RECRUITING
Children's Hospital New Orleans, New Orleans
RECRUITING
Ochsner Medical Center Jefferson, New Orleans
RECRUITING
University of Oklahoma Health Sciences Center, Oklahoma City
RECRUITING
Medical City Dallas Hospital, Dallas
RECRUITING
UT Southwestern/Simmons Cancer Center-Dallas, Dallas
RECRUITING
Cook Children's Medical Center, Fort Worth
RECRUITING
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston
RECRUITING
Children's Hospital of San Antonio, San Antonio
RECRUITING
Methodist Children's Hospital of South Texas, San Antonio
RECRUITING
Dell Children's Medical Center of Central Texas, Austin
RECRUITING
Texas Tech University Health Sciences Center-Amarillo, Amarillo
RECRUITING
Covenant Children's Hospital, Lubbock
RECRUITING
UMC Cancer Center / UMC Health System, Lubbock
RECRUITING
Children's Hospital Colorado, Aurora
RECRUITING
Saint Luke's Cancer Institute - Boise, Boise
RECRUITING
Primary Children's Hospital, Salt Lake City
RECRUITING
Phoenix Childrens Hospital, Phoenix
RECRUITING
Banner Children's at Desert, Mesa
RECRUITING
Alliance for Childhood Diseases/Cure 4 the Kids Foundation, Las Vegas
RECRUITING
Cedars Sinai Medical Center, Los Angeles
RECRUITING
Rady Children's Hospital - San Diego, San Diego
RECRUITING
Loma Linda University Medical Center, Loma Linda
RECRUITING
Children's Hospital of Orange County, Orange
RECRUITING
Valley Children's Hospital, Madera
RECRUITING
Lucile Packard Children's Hospital Stanford University, Palo Alto
RECRUITING
Kaiser Permanente-Oakland, Oakland
RECRUITING
University of California Davis Comprehensive Cancer Center, Sacramento
RECRUITING
Legacy Emanuel Children's Hospital, Portland
RECRUITING
Mary Bridge Children's Hospital and Health Center, Tacoma
RECRUITING
Providence Sacred Heart Medical Center and Children's Hospital, Spokane
RECRUITING
Providence Alaska Medical Center, Anchorage
RECRUITING
Arkansas Children's Hospital, Little Rock
RECRUITING
Maine Children's Cancer Program, Scarborough
RECRUITING
Dana-Farber Cancer Institute, Boston
RECRUITING
UMass Memorial Medical Center - University Campus, Worcester
RECRUITING
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center, Lebanon
RECRUITING
Hackensack University Medical Center, Hackensack
RECRUITING
Jersey Shore Medical Center, Neptune City
RECRUITING
Saint Peter's University Hospital, New Brunswick
RECRUITING
Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital, New Brunswick
RECRUITING
Newark Beth Israel Medical Center, Newark
RECRUITING
Rhode Island Hospital, Providence
RECRUITING
CancerCare Manitoba, Winnipeg
RECRUITING
IWK Health Centre, Halifax
RECRUITING
Children's Hospital of Eastern Ontario, Ottawa
RECRUITING
Hospital for Sick Children, Toronto
RECRUITING
Centre Hospitalier Universitaire Sainte-Justine, Montreal
RECRUITING
Centre Hospitalier Universitaire de Sherbrooke-Fleurimont, Sherbrooke
RECRUITING
CHU de Quebec-Centre Hospitalier de l'Universite Laval (CHUL), Québec
Children's Oncology Group
NETWORK