Effect of S. Aureus Skin Decolonization on Disease Severity in Atopic Dermatitis Patients

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

December 31, 2025

Primary Completion Date

December 31, 2028

Study Completion Date

December 31, 2028

Conditions
Atopic Dermatitis
Interventions
DRUG

Skin Cleanser Combination No.1

"1. Mupirocin 2% nasal ointment to the anterior nares to be applied twice daily~2. Chlorhexidine 4% topical soap (Hibiclens) to be used every other day in the shower or bath from the neck down and then completely rinsed.~3. Sulfamethoxazole/trimethoprim (Bactrim): one double strength (DS) tablet (800 mg/160 mg) twice per day for adolescents and adults. Dosing for pediatric patients will be calculated to 5 to 6 mg/kg trimethoprim also given twice daily."

Trial Locations (1)

02115

Boston Children's Hospital, Boston

All Listed Sponsors
lead

Boston Children's Hospital

OTHER