Deep Phenotyping of Peripheral Blood Cells and Circulating Factors in Metabolic Diseases

RecruitingOBSERVATIONAL
Enrollment

180

Participants

Timeline

Start Date

October 16, 2023

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
NAFLDDiabetes MellitusObesity
Interventions
DIAGNOSTIC_TEST

Oral glucose tolerance test

75g of a standardized glucose solution followed by blood draw at 0, 30, 60, 90, 120 min

DIAGNOSTIC_TEST

Liver Ultrasound

A crude assessment of liver status in order to identify the presence of steatosis or not will take place with ultrasound.

DIAGNOSTIC_TEST

Fibroscan of the Liver

FibroScan non-invasively measures the stiffness of the liver by capturing and calculating the speed of a shear wave as it travels through the liver (vibration controlled transient elastography).

DIAGNOSTIC_TEST

Magentic Resonance Imaging (MRI) of the liver

The exact calculation of liver fat with proton density fat fraction will take place with MRI.

Trial Locations (1)

01307

RECRUITING

University Study Center for Metabolic Diseases, Dresden

All Listed Sponsors
lead

Technische Universität Dresden

OTHER