Deep-sea Fish Oil for Prevention of Acute Radiation-induced Esophagitis

PHASE2RecruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

January 15, 2023

Primary Completion Date

March 15, 2024

Study Completion Date

April 15, 2026

Conditions
Radiation ToxicityEsophagitisEsophageal Cancer
Interventions
DRUG

Deep-sea fish oil

Starting from radiotherapy, the whole course of prophylactic oral deep-sea fish oil should be taken at the recommended dosage of 1g po bid according to the instructions (the administration method is to take it with the drug, remove the film on the drug surface, slowly swallow it in a supine position, and make the liquid fully contact with the esophageal mucosa). If no acute radioactive esophagus was assessed during the course of treatment, the patient was administered orally until the end of radiotherapy. If the patient developed radioactive esophagitis during the course of treatment, the relevant outcome measures were recorded and used as the endpoint event of the phase I study. The end point for patients without acute radiation esophagitis was at the completion of radiation therapy.

OTHER

Placebo

Take a capsule made of food oil that looks like deep-sea fish oil at a dose of 1g po bid. Treatment is discontinued when patients develop acute radiation esophagitis.

Trial Locations (1)

Unknown

RECRUITING

The First Affiliated Hospital of Chengdu Medical College, Chengdu

All Listed Sponsors
lead

First Affiliated Hospital of Chengdu Medical College

OTHER