Lactobacillus Rhamnosus GG Alleviates Oral Mucositis in Patients Undergoing Radiotherapy

NARecruitingINTERVENTIONAL
Enrollment

132

Participants

Timeline

Start Date

November 10, 2023

Primary Completion Date

March 31, 2025

Study Completion Date

March 31, 2025

Conditions
Oral Mucositis
Interventions
DIETARY_SUPPLEMENT

Lactobacillus rhamnosus GG powder

Lactobacillus rhamnosus GG powder (PROBIOTICS Powder, USA) contained no less than 5×10\^8 CFU viable cells of Lactobacillus rhamnosus GG as the active ingredient.

DIETARY_SUPPLEMENT

Placebo-containing tablets

Starch preparations that look and taste like Lactobacillus rhamnosus GG powder

RADIATION

Radiotherapy

One of the inclusion criteria for the study was that patients with squamous carcinoma of the head and neck (including nasopharyngeal carcinoma) needed to receive either radiotherapy alone or simultaneous radiotherapy and chemotherapy, with radiotherapy using intensity-modulated radiotherapy techniques.

Trial Locations (1)

610041

RECRUITING

West China Hospital, Sichuan University, Chengdu

All Listed Sponsors
lead

West China Hospital

OTHER