Effect of Esketamine on Conscious State in Patients With pDoC

NARecruitingINTERVENTIONAL
Enrollment

116

Participants

Timeline

Start Date

May 20, 2024

Primary Completion Date

December 31, 2025

Study Completion Date

June 30, 2026

Conditions
EsketamineConsciousness Disorders
Interventions
DRUG

Esketamine

Esketamine ( 50mg, dissolved in 50ml normal saline ) 0.3mg / kg will be infused intravenously at a constant speed within 30 min after tracheal intubation/pneumatectomy fixation.

DRUG

normal saline

Same amount of normal saline will be infused intravenously at a constant speed within 30 min after tracheal intubation/pneumatectomy fixation.

Trial Locations (1)

100070

RECRUITING

Beijing Tiantan Hospital, Capital Medical University, Beijing

All Listed Sponsors
lead

Beijing Tiantan Hospital

OTHER