ORal Antibiotics in Acute Mesenteric Ischemia

PHASE3RecruitingINTERVENTIONAL
Enrollment

196

Participants

Timeline

Start Date

January 31, 2025

Primary Completion Date

November 1, 2027

Study Completion Date

November 1, 2027

Conditions
Acute Mesenteric Ischemia
Interventions
DRUG

Gentamicin

Gentamicin 80 mg 3 times per day during 14 days oral route or nasogastric tube or jejunostomy tube (in the case of an ostomy)

DRUG

Placebo

Gentamicin placebo (2ml sodium chloride diluted 1/10 in a syringe of 20mL Metronidazole placebo in tablets

DRUG

Metronidazole

Métronidazole 500mg 3 times per day during 14 days oral route or nasogastric tube or jejunostomy tube (in the case of an ostomy)

Trial Locations (4)

75018

NOT_YET_RECRUITING

Chirurgie vasculaire, Paris

NOT_YET_RECRUITING

Réanimation Bichat, Paris

92110

RECRUITING

Gastroentérologie-Hépatologie Beaujon, Clichy

RECRUITING

Réanimation - Beaujon, Clichy

All Listed Sponsors
lead

Assistance Publique - Hôpitaux de Paris

OTHER