Efficacy and Safety of Longidaza® for the Treatment of Patients With Residual Changes in the Lungs After COVID-19

PHASE3CompletedINTERVENTIONAL
Enrollment

392

Participants

Timeline

Start Date

April 8, 2022

Primary Completion Date

December 31, 2023

Study Completion Date

December 31, 2023

Conditions
Post-Acute COVID-19 SyndromeLung Disease With PolymyositisFibrosisLung Diseases, InterstitialLung; Disease, Interstitial, With Fibrosis
Interventions
DRUG

Longidaza®

dose 3000 IU intramuscularly once every 5 days, 15 injections

DRUG

Placebo

intramuscularly once every 5 days, 15 injections

Trial Locations (30)

101990

"Federal State Budgetary Institution National Medical Research Center for Therapy and Preventive Medicine of the Ministry of Health of the Russian Federation", Moscow

111123

"Federal Budgetary Institution of Science Central Research Institute of Epidemiology of the Federal Service for Supervision of Consumer Rights Protection and Human Well-being", Moscow

119571

Unimed-S Zao, Moscow

119991

I.M. Sechenov First Moscow State Medical University, Moscow

150040

Medical Center for Diagnosis and Prevention plus LLC, Yaroslavl

150042

"The State Autonomous Healthcare Institution of the Yaroslavl region Clinical Hospital No. 9", Yaroslavl

194156

Energia Zdoroviya LLC, Saint Petersburg

194354

Medical Center Reavita Med SPb LLC, Saint Petersburg

Reavita Med SPb Medical Center LLC, Saint Petersburg

"St. Petersburg State Budgetary Healthcare Institution City Consultative and Diagnostic Center No. 1.", Saint Petersburg

196143

Eco-Safety Research Center LLC, Saint Petersburg

197110

"Federal State Budgetary Institution Consultative and Diagnostic Center with Polyclinic of the Office of the President of the Russian Federation", Saint Petersburg

198260

"St. Petersburg State Budgetary Healthcare Institution Consultative and Diagnostic Center No.85", Saint Petersburg

199226

Astarta LLC, Saint Petersburg

214006

"Regional State budgetary healthcare institution Clinical Hospital No. 1", Smolensk

394066

"Budgetary healthcare institution of the Voronezh region Voronezh Regional Clinical Hospital No. 1", Voronezh

410012

"Federal State Budgetary Educational Institution of Higher Education Saratov State Medical University named after V.I. Razumovsky of the Ministry of Health of the Russian Federation", Saratov

420012

"Federal State Budgetary Educational Institution of Higher Education Kazan State Medical University of the Ministry of Health of the Russian Federation. The State Autonomous healthcare institution Hospital for War Veterans of Kazan", Kazan'

"Federal State Budgetary Educational Institution of Higher Education Kazan State Medical University of the Ministry of Health of the Russian Federation", Kazan'

426061

Alliance Biomedical-Ural Group LLC, Izhevsk

454000

"Private healthcare institution Clinical Hospital RZD-Medicine of the city of Chelyabinsk", Chelyabinsk

454021

"State Budgetary Healthcare Institution Regional Clinical Hospital No. 3", Chelyabinsk

610027

"Federal State Budgetary Educational Institution of Higher Education Kirov State Medical University of the Ministry of Health of the Russian Federation", Kirov

614070

Professorial Clinic LLC, Perm

620039

Ural research Institute of Phthisiopulmonology, Yekaterinburg

624000

"State Autonomous Healthcare Institution of the Sverdlovsk region Aramil City Hospital", Aramil

630005

ErSi Medical LLC, Novosibirsk

634050

"Federal State Budgetary Educational Institution of Higher Education Siberian State Medical University of the Ministry of Health of the Russian Federation", Tomsk

650000

"State Autonomous Healthcare Institution Kuzbass Clinical Hospital of Emergency Medical Care named after M.A. Podgorbunsky", Kemerovo

650070

Medical Center Rhevma-Med LLC, Kemerovo

All Listed Sponsors
lead

NPO Petrovax

INDUSTRY