London Asthma Diagnostics Study

Not yet recruitingOBSERVATIONAL
Enrollment

225

Participants

Timeline

Start Date

June 30, 2024

Primary Completion Date

December 31, 2025

Study Completion Date

July 31, 2026

Conditions
Asthma
Interventions
DIAGNOSTIC_TEST

Oscillometry with reversibility testing

Oscillometry is a test that uses sound waves to measure the mechanical properties in the lungs during tidal breathing

DIAGNOSTIC_TEST

Breath volatile testing

We will be optimising and evaluating the sensitivity and specificity of a novel breath volatile organic compound test of a combination of reactive aldehydes using a gas chromatography-ion mobility spectrometry device

DIAGNOSTIC_TEST

Nasal eosinophil peroxidase

We will be evaluating the sensitivity and specificity of a novel nasal swab test for eosinophil peroxidase

DIAGNOSTIC_TEST

Handheld capnometry

We will be evaluating handheld capnometry (carbon dioxide breath testing) to diagnose adult asthma

Trial Locations (3)

W2 1PG

Imperial College Healthcare NHS Trust, London

W21NY

Imperial College Healthcare NHS Trust, London

NG7 2UH

Nottingham University Hospitals NHS Trust, Nottingham

All Listed Sponsors
collaborator

Asthma UK

OTHER

collaborator

General Practitioners Research Institute

NETWORK

lead

Imperial College London

OTHER