Speech in Noise Discrimination Skills in Multiple Sclerosis Patients.

NACompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

October 9, 2020

Primary Completion Date

March 23, 2023

Study Completion Date

April 23, 2023

Conditions
Multiple Sclerosis-Relapsing-Remitting
Interventions
DIAGNOSTIC_TEST

Hearing test

Hearing and speech tests of MS group and control group in the presence and absence of noise will be evaluated. Suppression test will be performed with OAE test in the presence and absence of noise.

DIAGNOSTIC_TEST

Speech in noise discrimination test

Speech discrimination in noise (SDN) test will be performed in a quiet room in accordance with the Industrial Acoustic Company (IAC) standard using the Grason-Stadler GSI 61 Clinical Audiometer. After pure tone audiometry and speech tests, the GKAE test will be performed. The speech in noise discrimination test will be performed with a signal-to-noise (S/N) ratio of +10 dB. A word list at 50 dB SL will be presented to the tested ear using live sound, while simultaneously white noise at 40 dB SL will be presented to the test ear (Beattie et al. 1997). This will be done for both ears. The speech in noise discrimination test scores will be calculated as percentages (%) for both ears.

DIAGNOSTIC_TEST

Montreal Cognitive Assessment Scale

Translated into Turkish as the Montreal Cognitive Assessment Scale and abbreviated as MOBID, MOCA assesses attention, executive/managerial functions, memory, visual-spatial skills, language, abstract thinking and arithmetic. It is easy and practical to apply. The score that can be obtained varies between 0-30. The cut-off point for cognitive impairment is 21. Patients who perform below 21 points are considered to have cognitive impairment. Although it is not a battery used in the MS patient group, a study conducted on 39 MS patients and 20 healthy people showed that it can be used safely for screening purposes in patients with MS (Aksoy et al., 2013; Nasreddine et al., 2005; Selekler \& Cangoz, 2009).

DIAGNOSTIC_TEST

Symbol Number Modalities Test (SDMT)

Attention, visuospatial information processing speed and working memory are assessed. It is one of the subtests of the Short Repeatable Neuropsychological Battery developed to assess cognitive functions in MS (Smith, 1973).

Trial Locations (1)

55300

Ondokuz Mayıs University, Samsun

All Listed Sponsors
lead

Asuman Kucukoner

OTHER

NCT06381297 - Speech in Noise Discrimination Skills in Multiple Sclerosis Patients. | Biotech Hunter | Biotech Hunter