ICP-248 in Combination with Orelabrutinib in Treatment-naïve Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

PHASE2/PHASE3RecruitingINTERVENTIONAL
Enrollment

226

Participants

Timeline

Start Date

May 15, 2024

Primary Completion Date

November 25, 2030

Study Completion Date

July 25, 2031

Conditions
Hematologic Malignancies
Interventions
DRUG

ICP-248

Eligible patients will receive ICP-248 orally as per the protocol,once daily for every 28 days as one treatment cycle

DRUG

Orelabrutinib

Eligible patients will receive Orelabrutinib orally as per the protocol,once daily for every 28 days as one treatment cycle

Trial Locations (50)

100191

RECRUITING

Peking University Third Hospital, Beijing

116023

RECRUITING

The Second Hospital of Dalian Medical University, Dalian

130061

RECRUITING

Bethune First Hospital of Jilin University, Changchun

200040

RECRUITING

Huashan Hospital, Shanghai

210029

RECRUITING

Jiangsu Province Hospital, Nanjing

213003

NOT_YET_RECRUITING

Changzhou First People's Hospital, Changzhou

223300

NOT_YET_RECRUITING

Huai'an First People's Hospital, Huai'an

230001

NOT_YET_RECRUITING

Anhui Provincial Hospital (The First Affiliated Hospital of University of Science and Technology of China), Hefei

230022

RECRUITING

The First Affiliated Hospital of Anhui Medical University, Hefei

233004

NOT_YET_RECRUITING

The First Affiliated Hospital of Bengbu Medical College, Bengbu

250012

NOT_YET_RECRUITING

Qilu Hospital of Shandong University, Jinan

250021

NOT_YET_RECRUITING

Shandong Provincial Hospital, Jinan

250117

RECRUITING

Shandong Cancer Hospital, Jinan

272011

NOT_YET_RECRUITING

Jining First People's Hospital, Jining

276002

RECRUITING

Linyi City Cancer Hospital, Linyi

300020

NOT_YET_RECRUITING

Blood Diseases Hospital of Chinese Academy of Medical Sciences, Tianjin

300181

RECRUITING

Tianjin Medical University Cancer Institute and Hospital, Tianjin

310003

RECRUITING

The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou

315040

NOT_YET_RECRUITING

The People's Hospital Affiliated to Ningbo University, Ningbo

330006

RECRUITING

The First Affiliated Hospital of Nanchang University, Nanchang

350001

RECRUITING

Fujian Medical University Union Hospital, Fuzhou

361003

RECRUITING

The First Affiliated Hospital of Xiamen University, Xiamen

400016

RECRUITING

The First Affiliated Hospital of Chongqing Medical University, Chongqing

400037

RECRUITING

Xinqiao Hospital, the Second Affiliated Hospital of Army Military Medical University, Chongqing

410012

RECRUITING

The Second Xiangya Hospital, Central South University, Changsha

410031

RECRUITING

Hunan Cancer Hospital, Changsha

430011

RECRUITING

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan

430022

RECRUITING

Union Hospital Tongji Medical College, Huazhong University of Science and Technology, Wuhan

443003

NOT_YET_RECRUITING

Yichang Central People's Hospital, Yichang

450003

RECRUITING

Henan Cancer Hospital, Zhenzhou

463599

RECRUITING

Henan Provincial People's Hospital, Zhengzhou

471003

NOT_YET_RECRUITING

The First Affiliated Hospital of Henan University of Science and Technology, Luoyang

473005

RECRUITING

Nanyang City Center Hospital, Nanyang

510055

RECRUITING

Sun Yat-sen University Cancer Center, Guangzhou

510515

NOT_YET_RECRUITING

Nanfang Hospital of Southern Medical University, Guangzhou

530021

NOT_YET_RECRUITING

The First Affiliated Hospital of Guangxi Medical University, Nanning

563003

NOT_YET_RECRUITING

The Affiliated Hospital of Zunyi Medical University, Zunyi

610041

NOT_YET_RECRUITING

West China Hospital of Sichuan University, Chengdu

610072

RECRUITING

Sichuan Provincial People's Hospital, Chengdu

644002

RECRUITING

Yibin Second People's Hospital, Yibin

650032

RECRUITING

The First Affiliated Hospital of Kunming Medical University, Kunming

710004

RECRUITING

The Second Affiliated Hospital of Xi'an Jiaotong University, Xi’an

710068

NOT_YET_RECRUITING

Shaanxi Provincial People's Hospital, Xi’an

730000

NOT_YET_RECRUITING

Gansu Provincial People's Hospital, Lanzhou

830000

RECRUITING

The Affiliated Cancer Hospital of Xinjiang Medical University, Ürümqi

050010

RECRUITING

The Fourth Hospital of Hebei Medical University, Shijiazhuang

063000

NOT_YET_RECRUITING

The Affiliated Hospital of North China University of Science and Technology, Tangshan

Liaoning

RECRUITING

Shengjing Hospital affiliated to China Medical University, Shenyang

030001

NOT_YET_RECRUITING

The Second Hospital of Shanxi Medical University, Taiyuan

030013

NOT_YET_RECRUITING

Shanxi Cancer Hospital, Taiyuan

All Listed Sponsors
lead

Beijing InnoCare Pharma Tech Co., Ltd.

INDUSTRY