"A Study of Auxora in Patients With AKI and Injurious Lung Crosstalk"

PHASE2RecruitingINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

July 1, 2024

Primary Completion Date

March 31, 2026

Study Completion Date

March 31, 2026

Conditions
Acute Kidney Injury
Interventions
DRUG

Auxora

1.25 mL/kg (2.0 mg/kg of zegocractin) intravenously (IV) over 4 hours at 0 hours, and then 1.0 mL/kg (1.6 mg/kg of zegocractin) IV over 4 hours at 24, 48, 72 and 96 hours for a total of 5 doses.

DRUG

Placebo

1.25 mL/kg IV over 4 hours at 0 hours and then 1.0 mL/kg IV over 4 hours at 24, 48, 72, and 96 hours for a total of 5 doses.

Trial Locations (43)

10016

RECRUITING

NYU Langone Health - Bellview, New York

RECRUITING

NYU Langone Health - Tisch Hospital, New York

11040

WITHDRAWN

Long Island Jewish Medical Center, Queens

11042

WITHDRAWN

Northshore University Hospital, New Hyde Park

11220

RECRUITING

NYU Langone Health - Brooklyn, Brooklyn

11794

RECRUITING

Stony Brook University Hospital, Stony Brook

17822

RECRUITING

Geisinger Medical Center, Danville

19140

RECRUITING

Temple University, Philadelphia

20010

WITHDRAWN

Medstar Washington Hospital Center, Washington D.C.

21201

WITHDRAWN

University of Maryland, Baltimore

22903

RECRUITING

University of Virginia, Charlottesville

29425

RECRUITING

Medical University of South Carolina, Charleston

30097

RECRUITING

Emory Johns Creek Hospital, Johns Creek

33606

RECRUITING

Tampa General, Tampa

34239

WITHDRAWN

Sarasota Memorial, Sarasota

35249

RECRUITING

University of Alabama, Birmingham

43202

RECRUITING

The Ohio State University, Columbus

44095

RECRUITING

Cleveland Clinic, Cleveland

44106

RECRUITING

University Hospitals Cleveland Medical Center, Cleveland

44307

RECRUITING

Cleveland Clinic Akron General, Akron

46202

RECRUITING

University of Indiana, Indianapolis

48109

WITHDRAWN

University of Michigan, Ann Arbor

48202

RECRUITING

Henry Ford, Detroit

48670

RECRUITING

My Michigan Health, Midland

52243

RECRUITING

University of Iowa, Iowa City

55101

WITHDRAWN

Regions Hospital, Saint Paul

60611

RECRUITING

Northwestern University-Pulmonary & Critical Care Medicine, Chicago

63401

RECRUITING

Hannibal Regional, Hannibal

65212

RECRUITING

University of Missouri, Columbia

72205

RECRUITING

University of Arkansas for Medical Sciences, Little Rock

75246

RECRUITING

Baylor Scott and White Research Institute, Dallas

77030

WITHDRAWN

Houston Methodist, Houston

RECRUITING

UT Houston, Houston

80045

RECRUITING

University of Colorado Hospital, Aurora

83712

RECRUITING

St Luke's Hospital, Boise

85224

RECRUITING

Chandler Regional Hospital, Chandler

90095

RECRUITING

UCLA, Los Angeles

90502

ACTIVE_NOT_RECRUITING

Torrance Memorial Medical Center, Torrance

90509

WITHDRAWN

Lundquist Institute for Biomedical Innovation at UCLA-Harbor Medical Center, Torrance

94304

RECRUITING

Stanford Health Care, Stanford

02115

RECRUITING

Brigham & Woman's Hospital, Boston

01805

RECRUITING

Lahey Hospital and Medical Center, Burlington

07666

RECRUITING

Holy Name, Teaneck

Sponsors

Lead Sponsor

All Listed Sponsors
lead

CalciMedica, Inc.

INDUSTRY