Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain

NARecruitingINTERVENTIONAL
Enrollment

470

Participants

Timeline

Start Date

March 10, 2025

Primary Completion Date

July 31, 2027

Study Completion Date

May 31, 2028

Conditions
PainSickle Cell Disease
Interventions
BEHAVIORAL

CBT+ Health coach

Participants will complete the pre-enrollment clinical screening measures (PHQ-9M, GAD-7, and PEG-3) and will repeat those assessments, as well as outcome assessments, at 3 months, 6 months, and 12 months. Participants in CBT w/ Health coach group will engage with the CaRISMA app to complete a daily pain and mood e-diary, daily record of opiate use, and weekly assessment of pain via the Painimation tool. In addition participants will have weekly contact with a peer health coach.

BEHAVIORAL

CBT w/o Health Coach ( self-guided)

Participants will complete the pre-enrollment clinical screening measures (PHQ-9M, GAD-7, and PEG-3) and will repeat those assessments, as well as outcome assessments, at 3 months, 6 months, and 12 months. Participants CBT w/o Health coach groups will engage with the CaRISMA app to complete a daily pain and mood e-diary, daily record of opiate use, and weekly assessment of pain via the Painimation tool.

BEHAVIORAL

Usual Care

Participants will complete the pre-enrollment clinical screening measures (PHQ-9M, GAD-7, and PEG-3) and will repeat those assessments, as well as outcome assessments, at 3 months, 6 months, and 12 months. Participants in the UC group will be asked to engage with the CaRISMA app to complete a daily pain and mood e-diary, daily record of opiate use, and weekly assessment of pain via the Painimation tool. All other care will be at the discretion of their treating provider

Trial Locations (12)

10065

RECRUITING

Weil Cornell Medical College, New York

14642

RECRUITING

University of Rochester Medical Center, Rochester

15213

RECRUITING

UPMC University of Pittsburgh Classical Hematology Adult Clinic, Pittsburgh

15224

RECRUITING

UPMC Children's Hospital of Pittsburgh, Pittsburgh

23284

RECRUITING

Virginia Commonwealth University, Richmond

27106

RECRUITING

Wake Forest Baptist Hospital, Durham

30345

RECRUITING

Children's Healthcare of Atlanta, Atlanta

36617

RECRUITING

University of South Alabama Medical Center, Mobile

90095

RECRUITING

UCLA Mattel Children's Hospital Ronald Reagan Hospital, Los Angeles

06106

RECRUITING

Connecticut Children's Medical Center, Hartford

48109-1079

RECRUITING

The Regents of the University of Michigan, Ann Arbor

07103

RECRUITING

Rutgers New Jersey Medical School, Newark

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

lead

University of Pittsburgh

OTHER