44
Participants
Start Date
April 15, 2024
Primary Completion Date
March 14, 2026
Study Completion Date
May 14, 2026
transcranial Alternating Current Stimulation
tACS will be performed by using a Conformite Europeenne (CE) marked stimulator device (Starstim ®, Neuroelectrics, Barcelona, Spain). By applying alternating current at the gamma frequency band (range 30-80), known to be associated to motor performance, tACS can entrain or synchronize neural oscillations in the targeted brain regions. By modulating cortical excitability of the cerebellum, a region strongly involved in motor learning and coordination, tACS is expected to influence the strength and coordination of motor responses elicited during the training. tACS will be delivered through two saline-soaked surface sponge electrodes (dimension: 25cm2 each), one placed over F3 (left frontal region) and the other over the right cerebellar hemisphere. The intensity will be set to 1mA, and this value will be gradually reached with a ramping-up phase of 30 secs. The frequency of the stimulation will match the IGF identified during the EEG recording performed at rest.
Scientific Institute, IRCCS E. Medea, Bosisio Parini
"IRCCS National Neurological Institute C. Mondino Foundation"
OTHER
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
OTHER
IRCCS Eugenio Medea
OTHER