Transcranial Alternating Current Stimulation in Cerebral Palsy (BOOSTTACS)

NANot yet recruitingINTERVENTIONAL
Enrollment

44

Participants

Timeline

Start Date

April 15, 2024

Primary Completion Date

March 14, 2026

Study Completion Date

May 14, 2026

Conditions
Cerebral Palsy
Interventions
DEVICE

transcranial Alternating Current Stimulation

tACS will be performed by using a Conformite Europeenne (CE) marked stimulator device (Starstim ®, Neuroelectrics, Barcelona, Spain). By applying alternating current at the gamma frequency band (range 30-80), known to be associated to motor performance, tACS can entrain or synchronize neural oscillations in the targeted brain regions. By modulating cortical excitability of the cerebellum, a region strongly involved in motor learning and coordination, tACS is expected to influence the strength and coordination of motor responses elicited during the training. tACS will be delivered through two saline-soaked surface sponge electrodes (dimension: 25cm2 each), one placed over F3 (left frontal region) and the other over the right cerebellar hemisphere. The intensity will be set to 1mA, and this value will be gradually reached with a ramping-up phase of 30 secs. The frequency of the stimulation will match the IGF identified during the EEG recording performed at rest.

Trial Locations (1)

23842

Scientific Institute, IRCCS E. Medea, Bosisio Parini

All Listed Sponsors
collaborator

"IRCCS National Neurological Institute C. Mondino Foundation"

OTHER

collaborator

Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia

OTHER

lead

IRCCS Eugenio Medea

OTHER

NCT06372041 - Transcranial Alternating Current Stimulation in Cerebral Palsy (BOOSTTACS) | Biotech Hunter | Biotech Hunter