A Randomized Phase II Basket Trial EXTENDing Efficacy of Systemic Therapy With Local Consolidative Therapy for OligoProgressive Metastatic Disease (EXTEND-OP)

PHASE2RecruitingINTERVENTIONAL
Enrollment

300

Participants

Timeline

Start Date

June 6, 2024

Primary Completion Date

October 10, 2028

Study Completion Date

October 10, 2030

Conditions
OligoProgressive Metastatic Disease
Interventions
PROCEDURE

Local Consolidation Therapy

Participants may receive radiation therapy. The choice of LCT and radiation therapy regimen will be determined by a multidisciplinary team including the study doctor.

PROCEDURE

Next-line Systemic Therapy

The specific next-line systemic therapy will be determined by your doctor.

Trial Locations (1)

77030

RECRUITING

MD Anderson Cancer Center, Houston

All Listed Sponsors
lead

M.D. Anderson Cancer Center

OTHER