Tunneled Peripherally Inserted Central Catheter (PICC) in Adult Patients and Associated Outcomes

NARecruitingINTERVENTIONAL
Enrollment

840

Participants

Timeline

Start Date

May 6, 2024

Primary Completion Date

December 31, 2025

Study Completion Date

July 31, 2026

Conditions
CLABSI - Central Line Associated Bloodstream InfectionDeep Vein ThrombosisDislodged CatheterOcclusionCatheter RuptureCatheter (Other); Complications
Interventions
PROCEDURE

Subcutaneous tunnelling

The Subcutaneous tunnelling group will undergo PICC placement under ultrasonography. Procedures will be implemented under hand hygiene, maximal sterile barrier, and chlorhexidine. The targeted arm will be sterilized with a mixture of chlorhexidine and isopropyl alcohol, and a sterile drape will be placed to cover the entire procedure feld from head to toe and place with additional subcutaneous tunnelling. After vein puncture with the access needle, a Nitinol guidewire will be placed as usual. We will make a tunnel distal to the initial venepuncture site using an additional 14-gauge needle. After resolution of the loop over the venepuncture site, a peel-away sheath will be placed over the wire. The catheter will be trimmed to the distance between the venepuncture site and cavoatrial junction plus the subcutaneous tunnel before being inserted in the usual manner.

PROCEDURE

Non-tunnelling

The Non-tunnelling group will have PICC placement with the traditional method under ultrasonography. Procedures will be implemented under hand hygiene, maximal sterile barrier, and chlorhexidine. The targeted arm will be sterilized with a mixture of chlorhexidine and isopropyl alcohol, and a sterile drape will be placed to cover the entire procedure feld from head to toe. After vein puncture with the access needle, a Nitinol guidewire will be placed. After, a peel-away sheath will be placed over the wire. The catheter will be trimmed to the distance between the venepuncture site and cavoatrial junction.

Trial Locations (1)

Unknown

RECRUITING

Hospital de Clínicas de Porto Alegre, Porto Alegre

All Listed Sponsors
collaborator

Hospital Moinhos de Vento

OTHER

collaborator

Irmandade Santa Casa de Misericórdia de Porto Alegre

OTHER

lead

Hospital de Clinicas de Porto Alegre

OTHER