Evaluation of PWI Assisted by Marshall Ethanolization in Ablation of Persistent Atrial Fibrillation

NARecruitingINTERVENTIONAL
Enrollment

260

Participants

Timeline

Start Date

December 1, 2023

Primary Completion Date

September 30, 2026

Study Completion Date

November 30, 2026

Conditions
Atrial Fibrillation
Interventions
PROCEDURE

VOMEI + PVI + linear ablation of mitral isthmus

The CS angiography is firstly performed to visualize the vein of Marshall. The ethanol infusion by anhydrous alcohol is then performed by using a guidewire and an OTW ballon. For radiofrequency catheter ablation, the standard procedure of pulmonary vein isolation is performed. All the enrolled persistent AF patients perform the routine linear ablation of mitral isthmus.

PROCEDURE

Posterior wall isolation

PWI is additionally performed for experimental group with linear ablation of LA roof and bottom line, and verified by mapping with a multielectrode catheter.

Trial Locations (1)

200092

RECRUITING

Xinhua Hospital, Shanghai Jiao Tong University, Shanghai

All Listed Sponsors
lead

Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

OTHER