220
Participants
Start Date
June 1, 2023
Primary Completion Date
December 31, 2025
Study Completion Date
December 31, 2025
supplementation of compound nutrients
Folic acid, vitamin B6, vitamin B12, and betaine per day orally for 12 weeks.
placebo control
The placebo is an excipient and the color, flavor, shape, taste, and weight are same with the tablet of supplement.
RECRUITING
SunYat-sen University, Guangzhou
Sun Yat-sen University
OTHER