Cisternostomy Vs Decompressive Craniectomy for Severe Traumatic Brain Injury

NANot yet recruitingINTERVENTIONAL
Enrollment

190

Participants

Timeline

Start Date

May 1, 2024

Primary Completion Date

May 1, 2025

Study Completion Date

May 1, 2025

Conditions
Severe Traumatic Brain Injury
Interventions
PROCEDURE

Decompressive Craniectomy

Patients allocated to this arm will undergo decompressive craniectomy, which involves the surgical removal of a section of the skull (bone flap). This procedure is performed to alleviate intracranial pressure (ICP) by providing additional space for the swollen brain to expand. The surgery will be performed by a single surgical team under general anesthesia. After the procedure, patients will be closely monitored for various parameters including duration on mechanical ventilation, duration of ICU stay, duration of hospital stay, and Glasgow Outcome Scale (GOS) at the time of discharge.

PROCEDURE

Cisternostomy

Patients allocated to this arm will undergo cisternostomy, a microsurgical technique used in neurosurgery. Cisternostomy involves the creation of an additional space for cerebrospinal fluid (CSF) circulation to alleviate brain edema and lower intracranial pressure (ICP). The surgery will be performed by the same surgical team under general anesthesia. Following the procedure, patients will be monitored for various parameters including duration on mechanical ventilation, duration of ICU stay, duration of hospital stay, and Glasgow Outcome Scale (GOS) at the time of discharge.

All Listed Sponsors
lead

University of Health Sciences Lahore

OTHER

NCT06363474 - Cisternostomy Vs Decompressive Craniectomy for Severe Traumatic Brain Injury | Biotech Hunter | Biotech Hunter