Plasma Biomarkers of Muscle Metabolism During Exercise to the Assessment of Insulin Resistance in CKD Dialysis Patients

NARecruitingINTERVENTIONAL
Enrollment

42

Participants

Timeline

Start Date

November 18, 2024

Primary Completion Date

November 18, 2026

Study Completion Date

November 18, 2026

Conditions
Metabolic SyndromeDialysis; Complications
Interventions
DIAGNOSTIC_TEST

Exercise test

"Metabolic effort test on cycloergometer with gas measurement. Gas exchanges (V'O2 and V'CO2) will be measured cycle-by-cycle using a gas analyzer connected to a flow meter Measurements will be taken every 6 minutes, at rest and during exercise on a cycloergometer, in five 6-minute increments, corresponding to intensities of 0% (rest), 20%, 30%, 40%, 50 and 60% of the subject's estimated maximum power, for a total duration of around 45 minutes."

DIAGNOSTIC_TEST

Blood sample

"A catheter will be placed in a forearm vein to take blood samples at rest and at the end of the 5-stage stress test.~Sampling times synchronized with stress test measurements"

DIAGNOSTIC_TEST

Impedancemetry

measurement of anthropometric data (weight, height, waist circumference). impedancemetry will enable body composition to be analyzed by placing surface electrodes on the body. The participant will lie on an examination table and must remain at rest for 5 minutes.

Trial Locations (2)

34295

RECRUITING

AIDER Santé Fondation Charles Mion Montpellier, site Lapeyronie, Montpellier

RECRUITING

Montpellier University Hospital, Montpellier

All Listed Sponsors
lead

University Hospital, Montpellier

OTHER