Topical Tretinoin Prophylaxis for Anti-EGFR Induced Skin Toxicity in Metastatic Colorectal Cancer

PHASE2RecruitingINTERVENTIONAL
Enrollment

25

Participants

Timeline

Start Date

February 19, 2025

Primary Completion Date

July 31, 2027

Study Completion Date

July 31, 2029

Conditions
Metastatic Colon CancerMetastatic Rectum Cancer
Interventions
DRUG

Topical Tretinoin

Topical tretinoin will be applied to one half of the face, either left or right side. The side the topical tretinoin will be applied to will be randomized.

OTHER

Placebo

A placebo (topical moisturizer) will be applied to the other half of the face, either left or right side. The side the topical tretinoin will be applied to will be randomized.

Trial Locations (1)

84112

RECRUITING

Huntsman Cancer Institute at University of Utah, Salt Lake City

All Listed Sponsors
lead

University of Utah

OTHER