The Remineralization of Early Enamel Caries in Permanent Teeth

PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

June 6, 2024

Primary Completion Date

November 6, 2024

Study Completion Date

January 6, 2025

Conditions
White Spot Lesion
Interventions
DRUG

self assembling peptide p11-4 with fluoride

"Self-assembling peptide (P11-4) fluoride plus will be applied according to the manufacturer's instructions by pushing the two cylinders together and will left for 5 min till the tooth surface appears dry to insure its diffusion~The remineralizing process of the early enamel carious lesions will be assessed quantitatively using the laser fluorescence DIAGNOdent measuring and assessed qualitatively using ICDAS II scoring system at baseline 1, 3, 6 months post-treatment"

DRUG

5% sodium fluoride varnish

Fluoride varnish will be applied under manufacturer instructions by applying thin layer of varnish with a brush in strokes The remineralizing process of the early enamel carious lesions will be assessed quantitatively using the laser fluorescence DIAGNOdent measuring and assessed qualitatively using ICDAS II scoring system at baseline 1, 3, 6 months post-treatment

Trial Locations (1)

31511

faculty of Dentistry,Tanta university, Tanta

All Listed Sponsors
lead

Tanta University

OTHER

NCT06358066 - The Remineralization of Early Enamel Caries in Permanent Teeth | Biotech Hunter | Biotech Hunter