NCT06356571 - A Study to Investigate Subcutaneous Isatuximab in Combination With Weekly Carfilzomib and Dexamethasone in Adult Participants With Relapsed and/or Refractory Multiple Myeloma | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

March 17, 2025

Primary Completion Date

January 8, 2027

Study Completion Date

July 15, 2027

Conditions

Plasma Cell Myeloma Refractory

Interventions

DRUG

Isatuximab SC-OBDS

Pharmaceutical form:Solution for SC-OBDS administration-Route of administration:SC-OBDS

DRUG

Montelukast

Pharmaceutical form:As per local commercial product-Route of administration:Oral

DRUG

Dexamethasone

Pharmaceutical form:As per local commercial product-Route of administration:Oral or IV

DRUG

Acetaminophen

Pharmaceutical form:As per local commercial product-Route of administration:Oral or IV

DRUG

Diphenhydramine

Pharmaceutical form:As per local commercial product-Route of administration:Oral (as premedication) or IV/oral equivalent (for management of infusion reaction)

DRUG

Methylprednisolone

Pharmaceutical form:As per local commercial product-Route of administration:IV

DRUG

Carfilzomib

Pharmaceutical form:As per local commercial product-Route of administration:IV

Trial Locations (16)

10065

RECRUITING

Memorial Sloan Kettering Cancer Center - New York - York Avenue- Site Number : 8400003, New York

29615

RECRUITING

Prisma Health - Eastside Office- Site Number : 8400019, Greenville

33024

RECRUITING

Millennium Oncology- Site Number : 8400011, Pembroke Pines

33063

RECRUITING

D&H Cancer Research Center- Site Number : 8400049, Margate

33324

RECRUITING

BRCR Global- Site Number : 8400008, Plantation

37909

RECRUITING

Tennessee Cancer Specialist- Site Number : 8400035, Knoxville

37920

RECRUITING

University of Tennessee Medical Center- Site Number : 8400006, Knoxville

44718

RECRUITING

Gabrail Cancer Center- Site Number : 8400010, Canton

48073

RECRUITING

Michigan Hematology and Oncology Consultants- Site Number : 8400039, Royal Oak

48126

RECRUITING

Michigan Hematology and Oncology Consultants- Site Number : 8400036, Dearborn

53715

RECRUITING

SSM Health - Dean Medical Group South Madison Campus- Site Number : 8400009, Madison

70433

RECRUITING

Pontchartrain Cancer Center- Site Number : 8400046, Covington

87401

RECRUITING

San Juan Oncology Associates- Site Number : 8400016, Farmington

90069

RECRUITING

Berenson Cancer Center- Site Number : 8400044, West Hollywood

06511

RECRUITING

Smilow Cancer Center at Yale-New Haven- Site Number : 8400020, New Haven

07601

RECRUITING

Hackensack Meridian Health - Hackensack University Medical Center- Site Number : 8400021, Hackensack