A Nerve Block Therapy for Bulbar Palsy Pharyngeal Dysphagia

NACompletedINTERVENTIONAL
Enrollment

122

Participants

Timeline

Start Date

January 1, 2022

Primary Completion Date

May 2, 2023

Study Completion Date

May 31, 2023

Conditions
Bulbar Palsy
Interventions
PROCEDURE

Nerve Block

The percutaneous approach via the paratracheal route was used for Stellate ganglion block. The operator stood on the side of the block, instructed the patient to lie supine with a thin pillow placed below the shoulders, and tilted the head 45° towards the blocked side, fully exposing the neck. Then, routine disinfection of the neck skin was performed. The puncture site was located 2.5 cm above the sternoclavicular joint and 1.5 cm lateral to the midline of the neck.

DRUG

Lidocaine Hydrochloride

the patients were provided with Stellate ganglion block, using 1.5ml of 2% Lidocaine hydrochloride (1ml: 0.5mg) and 500ug of Vitamin B12 (1ml: 0.5g).

BEHAVIORAL

routine therapy

"All the participants are provided with the comprehensive rehabilitation (routine rehabilitation and swallowing function training). The routine rehabilitation included intervention for risk factors (blood pressure, blood lipids, blood glucose, smoking and alcohol restriction, exercise, etc.).~Regrading swallowing function training, both groups are given swallowing function training, including 1) exercises of closure of the vocal folds, pharyngeal, and laryngeal muscles exercises, and respiratory muscle strength training, for 15 min each time and twice per day. 2) isotonic/isometric swallowing exercises, supraglottic swallowing exercises, for 20 min each time and twice per day. 3) effortful swallowing exercises, and cough reflex training, for 10 min each time and twice per day."

PROCEDURE

placebo block

the patients were provided with normal saline. The percutaneous approach via the paratracheal route was used for Stellate ganglion block. The operator stood on the side of the block, instructed the patient to lie supine with a thin pillow placed below the shoulders, and tilted the head 45° towards the blocked side, fully exposing the neck. Then, routine disinfection of the neck skin was performed. The puncture site was located 2.5 cm above the sternoclavicular joint and 1.5 cm lateral to the midline of the neck.

Trial Locations (1)

Unknown

ZhenD No.1 Hos., Zhenzhou

All Listed Sponsors
lead

Babujinaya Cela

OTHER_GOV

NCT06347250 - A Nerve Block Therapy for Bulbar Palsy Pharyngeal Dysphagia | Biotech Hunter | Biotech Hunter