To Evaluate the Safety and Efficacy of MANP in Subjects With Difficult to Control/ Resistant Hypertension

PHASE2RecruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

November 17, 2024

Primary Completion Date

July 1, 2026

Study Completion Date

September 1, 2026

Conditions
Difficult to Control Hypertension
Interventions
DRUG

MANP

MANP (modified atrial natriuretic peptide) is a peptide that is being developed for treatment of difficult to control/resistant hypertension.

OTHER

Placebo Matched control

This is a placebo matched vehicle - Vehicle minus the active ingredient

Trial Locations (29)

19114

ACTIVE_NOT_RECRUITING

Tristar Clinical Investigations, P.C., Philadelphia

27577

RECRUITING

Superior Clinical Research, Smithfield

28112

RECRUITING

Monroe Biomedical Research, Monroe

30092

RECRUITING

Alta Pharmaceutical Research Center, Peachtree Corners

30101

RECRUITING

Cowry Health, Acworth

32117

RECRUITING

Arrow Clinical Trials, Daytona Beach

33021

RECRUITING

Royal Research Corp, Hollywood

33122

RECRUITING

Evolution Clinical Trials, Miami

33161

RECRUITING

SM Research Center, Biscayne Park

43302

RECRUITING

K&R Research LLC, Marion

48126

RECRUITING

Revival Research Institute, LLC, Dearborn

48504

RECRUITING

Aa Mrc Llc, Flint

60607

RECRUITING

Cedar Crosse Research Center, Chicago

72204

RECRUITING

Lynn Institute of the Ozarks, Little Rock

75019

ACTIVE_NOT_RECRUITING

Prime Research, Coppell

75075

RECRUITING

Clinical Investigations of Texas, Plano

75092

RECRUITING

Revival Research, Sherman

75230

RECRUITING

Dallas Renal Group, Dallas

76063

RECRUITING

Prime Clinical Research, Mansfield

77002

RECRUITING

East Texas Cardiology, Houston

77099

RECRUITING

Pioneer Research Solutions, Houston

77407

RECRUITING

Aavon Clinical Trials, Richmond

90211

RECRUITING

Amicis Research Center - Beverly Hills, Beverly Hills

91308

WITHDRAWN

Interventional Cardiology Medical Group, West Hills

91344

RECRUITING

Amicis Research Center - Granada Hills, Granada Hills

91355

RECRUITING

Amicis Research Site - Valencia, Valencia

91361

RECRUITING

Office of Dr. Edward Portnoy MD, Westlake Village

92630

RECRUITING

Orange County Research Center, Lake Forest

93551

RECRUITING

Amicis Research Center - Palmdale, Palmdale

Sponsors
All Listed Sponsors
collaborator

Mayo Clinic

OTHER

collaborator

PPD Development, LP

INDUSTRY

lead

E-Star BioTech, LLC

INDUSTRY

NCT06343298 - To Evaluate the Safety and Efficacy of MANP in Subjects With Difficult to Control/ Resistant Hypertension | Biotech Hunter | Biotech Hunter