Impact of Metabolic Flexibility on Changes in Metabolic Health

CompletedOBSERVATIONAL
Enrollment

18

Participants

Timeline

Start Date

October 9, 2024

Primary Completion Date

August 25, 2025

Study Completion Date

August 27, 2025

Conditions
ObesityMetabolic Syndrome
Interventions
DIAGNOSTIC_TEST

Metabolic flexibility in the fasted state

Measured at baseline during the InSight study (2008-2009). Calculated as the respiratory exchange ratio in the fasting state adjusted for the circulating concentrations of free fatty acids

OTHER

Metabolic flexibility in euglycemic-hyperinsulinemic clamp

Measured at baseline during the InSight study (2008-2009). Calculated as the change in respiratory exchange ratio adjusted for glucose disposal rate

OTHER

Metabolic flexibility in the metabolic chamber

Measured at baseline during the InSight study (2008-2009). Calculated as the difference between awake respiratory exchange ratio (from 8 a.m. to 11 p.m.) and sleeping respiratory exchange ratio during a 23-hour stay in the metabolic chamber

Trial Locations (1)

70808

Pennington Biomedical Research Center, Baton Rouge

All Listed Sponsors
lead

Pennington Biomedical Research Center

OTHER

NCT06340321 - Impact of Metabolic Flexibility on Changes in Metabolic Health | Biotech Hunter | Biotech Hunter