A Study of Lebrikizumab (LY3650150) in Adult Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP)

PHASE3RecruitingINTERVENTIONAL
Enrollment

510

Participants

Timeline

Start Date

April 29, 2024

Primary Completion Date

May 31, 2027

Study Completion Date

March 31, 2028

Conditions
Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
Interventions
DRUG

LY3650150

Administered SC.

DRUG

Placebo

Administered SC.

DRUG

Standard therapy for INCS

Administered as intranasal spray.

Trial Locations (174)

1200

NOT_YET_RECRUITING

Cliniques Universitaires Saint-Luc Avenue Hippocrate 10, Woluwe-Saint-Lambert

1202

RECRUITING

Diagnostic-Consultative Centre Ascendent EOOD, Sofia

1431

RECRUITING

Multiprofile Hospital For Active Treatment Dr Tota Venkova A, Gabrovo

NOT_YET_RECRUITING

Military Medical Academy - Multiprofile Hospital for Active Treatment - Sofia,, Sofia

1504

NOT_YET_RECRUITING

Multiprofile Hospital for Active treatment Trakia EOOD, Zagora

1527

RECRUITING

University Multiprofile Hospital for Active Treatment Tsaritsa Yoanna, Sofia

2000

NOT_YET_RECRUITING

Centro Respiratorio Infantil, Santa Fe

5101

RECRUITING

Pneumocare, Erpent

5800

NOT_YET_RECRUITING

Medical Center Medconsult Pleven OOD, Pleven

7061

RECRUITING

SMG-SNU Boramae Medical Center, Seoul

8022

RECRUITING

Centro Médico Teknon, Barcelona

8200

RECRUITING

Aarhus University Hospital, Dept. of Ear-Nose-Throat, Aarhus

9000

NOT_YET_RECRUITING

UZ Gent, Ghent

10002

RECRUITING

National Taiwan University Hospital, Taipei

10016

RECRUITING

Madison ENT & Facial Plastic Surgery, New York

10117

NOT_YET_RECRUITING

Charite-Universitatsmedizin Berlin, Berlin

10455

NOT_YET_RECRUITING

Equity Medical, The Bronx

10629

RECRUITING

HNO Zentrum am Kudamm, Berlin

11407

RECRUITING

Hospital Universitario de Jerez, Cadiz

13496

NOT_YET_RECRUITING

CHA Bundang Medical Center, Gyeonggi-do

13620

RECRUITING

Seoul National University Bundang Hospital, Seongnam-si

14142

RECRUITING

Delta Health Care S.R.L, Bucharest

RECRUITING

Delta Health Care S.R.L, Bucharest

15706

NOT_YET_RECRUITING

Hospital Clínico Universitario de Santiago, Galícia

16499

RECRUITING

Ajou University Hospital, Suwon

18017

NOT_YET_RECRUITING

Specialty Physician Associates, Bethlehem

20132

NOT_YET_RECRUITING

Ospedale San Raffaele, Milan

20871

RECRUITING

ASST Brianza - Vimercate Hospital, Vimercate

21162

NOT_YET_RECRUITING

Chesapeake Clinical Research, Inc., White Marsh

23235

NOT_YET_RECRUITING

Richmond Ear Nose and Throat, Richmond

23507

NOT_YET_RECRUITING

Eastern Virginia Medical School, Norfolk

23538

NOT_YET_RECRUITING

Universitätsklinikum Schleswig-Holstein, Lübeck

23561

RECRUITING

Taipei Medical University Shuang Ho Hospital, New Taipei City

28002

RECRUITING

FutureMeds DKF, Madrid

28040

RECRUITING

Hospital Universitario Fundación Jiménez Díaz, Madrid

29425

NOT_YET_RECRUITING

Medical University of South Carolina- Department of Otolaryngology and Head and Neck Surgery, Charleston

30001

RECRUITING

The First Hospital of Shanxi Medical University, Taiyuan

31008

NOT_YET_RECRUITING

Clinica Universidad de Navarra, Pamplona

32825

NOT_YET_RECRUITING

Orlando ENT & Allergy, Orlando

33060

NOT_YET_RECRUITING

NuLine Clinical Trial Center, Pompano Beach

33613

NOT_YET_RECRUITING

University of South Florida, Tampa

35128

RECRUITING

Azienda Ospedaliera Di Padova, Padua

35209

NOT_YET_RECRUITING

AllerVie Clinical Research, Birmingham

35233

RECRUITING

University of Alabama at Birmingham, Birmingham

41009

RECRUITING

Hospital Universitario Virgen de la Macarena Avenida Dr. Fedriani, Andalucia

43235

RECRUITING

Optimed Research, LTD, Columbus

45267

NOT_YET_RECRUITING

UCMC, Cincinnati

48108

RECRUITING

Inje University Haeundae Paik Hospital, Busan

49241

RECRUITING

Pusan National University Hospital, Pusan

50134

NOT_YET_RECRUITING

AOU Careggi- University of Florence, Florence

56126

NOT_YET_RECRUITING

Azienda Ospedaliero Universitaria Pisana - Stabilimento Santa Chiara, Pisa

60596

NOT_YET_RECRUITING

IKF Pneumologie, Frankfurt am Main

60657

RECRUITING

Chicago ENT, Chicago

63141

NOT_YET_RECRUITING

Washington University School of Medicine, St Louis

65212

NOT_YET_RECRUITING

University of Missouri, Columbia

70471

RECRUITING

South Louisiana Ear, Nose, Throat & Facial Plastic Surgery - PPDS, Mandeville

77030

RECRUITING

University of Texas Physicians Department of Otorhinolaryngology Clinc, Houston

80131

RECRUITING

AOU Federico II Via Pansini, Napoli

80923

RECRUITING

Colorado ENT & Allergy, Colorado Springs

83706

RECRUITING

Treasure Valley Medical Research, Boise

90503

NOT_YET_RECRUITING

Breathe Clear Institute, Torrance

91007

NOT_YET_RECRUITING

Keck Medicine of USC, Arcadia

92697

RECRUITING

University of California, Irvine, Irvine

95661

RECRUITING

DaVinci Research LLC, Roseville

100191

RECRUITING

Peking University Third Hospital, Beijing

100730

NOT_YET_RECRUITING

Beijing Hospital, Beijing

RECRUITING

Beijing Tongren Hospital, Beijing

110004

RECRUITING

Shengjing Hospital of China Medical University, Shenyang

134001

NOT_YET_RECRUITING

Tonghua Central Hospital, Tonghua

200222

RECRUITING

Centrul de Excelenta in Rinologie S.R.L, Dolj

221006

RECRUITING

The Affiliated Hospital of Xuzhou Medical University, Xuzhou

223300

RECRUITING

Huai'an First People's Hospital, Huai'an

233004

NOT_YET_RECRUITING

The First Affiliated Hospital of Bengbu Medical College, Bengbu

250014

RECRUITING

The first Affilliated Hospital Shandong First Medical University, Shandong

300121

RECRUITING

Tianjin People's Hospital, Tianjin

325038

RECRUITING

The 2nd Affiliated Hospital of Wenzhou Medical University, Wenzhou Avenue

330006

RECRUITING

The First Affiliated Hospital of Nanchang University, Nanchang

350000

RECRUITING

The First Affiliated Hospital Of Fujian Medical University, Fuzhou

400015

RECRUITING

Cardiomed S.R.L, Cluj-Napoca

410013

RECRUITING

The Third Xiangya Hospital of Central South University, Changsha

430022

RECRUITING

Union Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan

430060

RECRUITING

Renmin Hospital of Wuhan University, Wuhan

500091

RECRUITING

Centrul Medical Unirea SRL, Brasov

500450

RECRUITING

Centrul Medical De Diagnostic Si Tratament Ambulator Neomed S.R.L, Brasov

RECRUITING

Centrul Medical De Diagnostic Si Tratament Ambulator Neomed S.R.L, Brasov

528000

RECRUITING

The First People's Hospital of Foshan, Foshan

530021

RECRUITING

The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning

570311

NOT_YET_RECRUITING

Hainan General Hospital, Haikou

610072

RECRUITING

Sichuan Provincial People's Hospital, Chengdu

750002

RECRUITING

First People's Hospital of Yinchuan, Yinchuan

800168

RECRUITING

Fondazione Policlinico A. Gemelli IRCCS, Rome

02215

RECRUITING

Brigham and Women's Hospital, Boston

75390-9035

NOT_YET_RECRUITING

UT Southwestern Medical Center, Dallas

75070-5735

RECRUITING

Ear Nose and Throat Associates of Texas PA, McKinney

78258-3227

RECRUITING

Alamo ENT Associates, San Antonio

53226-3548

NOT_YET_RECRUITING

The Medical College of Wisconsin, Milwaukee

B7240KJB

NOT_YET_RECRUITING

CEMLO - Centro de Especialidades Médicas Lobos, Beunos Aires

C1426BP

NOT_YET_RECRUITING

Fundacion Respirar, Buenos Aires

Unknown

NOT_YET_RECRUITING

Centro Platense en Investigaciones Respiratorias - CEPIR, Buenos Aires

NOT_YET_RECRUITING

CIMER-Centro Integral de Medicina Respiratoria, San Miguel de Tucumán

NOT_YET_RECRUITING

CSAC, Québec

RECRUITING

Shenzhen Second People's Hospital, Guangdong

RECRUITING

Hangzhou First People's Hospital, Hangzhou

NOT_YET_RECRUITING

Ningbo Medical Center Lihuili Hospital, Ningbo

RECRUITING

Tongji Hospital of Tongji University, Shanghai

NOT_YET_RECRUITING

Aalborg Universitetshospital Medicinerhuset Lungemedicinsk Forskningsenhed, Aalborg

NOT_YET_RECRUITING

Bispebjerg Hospital Department of Respiratory Medicine, Copenhagen

RECRUITING

Sjællands Universitets Hospital, Køge

RECRUITING

Toyota Memorial Hospital, Aichi

RECRUITING

Clinic Kashiwanoha, Chiba

NOT_YET_RECRUITING

University of Fukui Hospital, Fukui

RECRUITING

Ibaraki Prefectural Central Hospital, Ibaraki

RECRUITING

Tohoku Medical and Pharmaceutical University Hospital, Miyagi

NOT_YET_RECRUITING

WIM-PIB, Warsaw

NOT_YET_RECRUITING

Unidade Local de Saúde Loures-Odivelas, Loures

C1121ABE

NOT_YET_RECRUITING

Fundacion CIDEA, Caba

CP 2000

NOT_YET_RECRUITING

Centro de Investigaciones Clínicas - IESR - Rosario, Rosario

CP4000

NOT_YET_RECRUITING

Investigaciones en Patologías Respiratorias SRL, San Miguel de Tucumán

C1414AIF

NOT_YET_RECRUITING

CARE - Centro de Alergia y Enfermedades Respiratorias, Villa Crespo

N6A 4V2

NOT_YET_RECRUITING

St. Joseph's Hospital, Ontario

V5Z 1M9

NOT_YET_RECRUITING

The Gordon and Leslie Diamond Health Care Centre, Vancouver

V6Z 1Y6

NOT_YET_RECRUITING

St Paul's Sinus Centre, Vancouver

01139

RECRUITING

Praxis für HNO und Allergologie, Dresden

74, 01307

RECRUITING

Universitätsklinikum Carl Gustav Carus an der TU Dresden, Dresden

07747

NOT_YET_RECRUITING

Universitätsklinikum Jena, Jena

01067

RECRUITING

HNO Praxis, Sachsen

409-3821

RECRUITING

University of Yamanashi Hospital, Chūō

810-0001

NOT_YET_RECRUITING

Saiseikai Fukuoka General Hospital, Fukuoak

812-0053

RECRUITING

Matsuda Hospital, Fukuoka

812-8582

RECRUITING

Kyushu University Hospital, Fukuoka

583-8588

RECRUITING

Osaka Habikino Medical Center, Habikino-shi

573-1191

NOT_YET_RECRUITING

Kansai Medical University Hospital, Hirakata

663-8131

NOT_YET_RECRUITING

Hyogo Medical University Hospital, Hyōgo

665-0827

RECRUITING

Takarazuka City Hospital, Hyōgo

890-0062

RECRUITING

Kagoshima Kouseiren Hospital, Kagoshima

231-0801

RECRUITING

Yokohama City Minato Red Cross Hospital, Kanagawa

250-8558

RECRUITING

Odawara Municipal Hospital, Kanagawa

292-8535

RECRUITING

Kimitsu Chuo Hospital, Kisarazu

806-8501

RECRUITING

1-8-1, Kishinoura, Kitakyushu

860-0814

RECRUITING

3-54-2, Kotohirahommachi, Kumamoto

400-0405

RECRUITING

Kyosai Hospital, Minami-Alps

395-0056

RECRUITING

Ritsuzankai Iida Hospital, Nagano

940-8621

RECRUITING

Asahioka, 1-24, Niigata

951-8520

RECRUITING

Niigata University Medical & Dental Hospital, Niigata

553-0003

RECRUITING

Japan Community Health care Organization Osaka Hospital, Osaka

RECRUITING

Kansai Electric Power Hospital, Osaka

420-0853

RECRUITING

8-2 Otemachi, Shizuoka

153-8515

RECRUITING

Toho University Ohashi Medical Center, Tokyo

173-0032

RECRUITING

Nihon University Itabashi Hospital, Tokyo

514-8507

RECRUITING

Mie University Hospital, Tsu

750-0061

RECRUITING

JCHO Shimonoseki Medical center, Yamaguchi

15-879

RECRUITING

Niepubliczny Zakład Opieki Zdrowotnej E-Vita, Bialystok

40-081

RECRUITING

Centrum Medyczne Pratia Katowice, Katowice

40-611

RECRUITING

Centrum Medyczne Angelius Provita, Katowice

25-426

RECRUITING

B&R Clinical Sp. z o.o, Kielce

30-033

RECRUITING

Centrum Medyczne All-Med, Krakow

31-513

RECRUITING

Centrum Medyczne Promed ul. Olszańska 5G, Krakow

60-693

RECRUITING

Specjalistyczny Niepubliczny Zakład Opieki Zdrowotnej Alergologia Plus Ośrodek Diagnostyki, Poznan

32-020

RECRUITING

Centrum Medyczne Biotamed Morawska Barbara, Wieliczka

50-220

RECRUITING

EMC INSTYTUT MEDYCZNY S.A. Przychodnia, Wroclaw

52-416

RECRUITING

Centrum Medyczne Oporów, Wroclaw

4710-243

NOT_YET_RECRUITING

Centro Clínico Académico - Braga (2CA-Braga) (Hospital de Braga), Braga

4464-513

NOT_YET_RECRUITING

Hospital Pedro Hispano, Senhora da Hora

02841

RECRUITING

Korea University Anam Hospital, Seoul

03080

RECRUITING

SNUH - Seoul National University Hospital, Seoul

06591

RECRUITING

The Catholic University of Korea, Seoul

08308

NOT_YET_RECRUITING

Korea University Guro Hospital, Seoul

BS2 8HW

RECRUITING

Bristol Royal Infirmary University Hospitals, Bristol

W6 8RF

NOT_YET_RECRUITING

Charing Cross Hospital, Chelsea

NR31 6LA

RECRUITING

James Paget University Hospitals NHS Foundation Trust, Great Yarmouth

RG1 5AN

RECRUITING

Royal Berkshire NHS Foundation Trust, London

SE1 7EH

RECRUITING

Guys and St Thomas' NHS Foundation Trust, London

NE7 7DN

NOT_YET_RECRUITING

Newcastle upon Tyne Hospitals NHSFT Freeman Hospital, Newcastle upon Tyne

SK2 7JE

RECRUITING

Stepping Hill Hospital, Stockport

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