NCT06336213View on ClinicalTrials.gov

Antibacterial Tactics Based on Presepsin Level in Thoracic Aorta Surgery Patients

NARecruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

February 19, 2024

Primary Completion Date

November 1, 2025

Study Completion Date

December 15, 2025

Conditions
Aortic Aneurysm and DissectionCardiac Valve DiseaseThoracic Aortic AneurysmThoracic Aortic Dissection
Interventions
DRUG

Ampicillin-sulbactam

If a patient meets dual criteria (presepsin \> 519,5 pg/ml at the end of surgery and the absence of presepsin increase after 6 hours after the end of surgery) then switching to ampicillin/sulbactam 3 g every 6 hours at least 72 h after the surgery is done.

Trial Locations (1)

119991

RECRUITING

Petrovsky Research National Centre of Surgery (Petrovsky NRCS), Moscow

All Listed Sponsors
lead

Petrovsky National Research Centre of Surgery

OTHER