Cognitive Decline and Underlying Mechanisms in Symptomatic Intracranial Artery Stenosis Patients: A Cohort Study

RecruitingOBSERVATIONAL
Enrollment

100

Participants

Timeline

Start Date

November 1, 2022

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2026

Conditions
Intracranial AtherosclerosisCognitive ImpairmentCerebrovascular Event
Interventions
DRUG

Aspirin Tablet, Clopidogrel Bisulfate Tablets and Atorvastatin

All patients received standard medical management, including dual antiplatelet therapy (aspirin and clopidogrel) for three months with aspirin or clopidogrel monotherapy thereafter and high-dose statin, and treatment of hypertension to guideline targets.

PROCEDURE

Endovascular therapy,Aspirin Tablet, Clopidogrel Bisulfate Tablets and Atorvastatin

All patients underwent endovascular therapy and received standard medical management after surgery, including dual antiplatelet therapy (aspirin and clopidogrel) for three months with aspirin or clopidogrel monotherapy thereafter and high-dose statin, and treatment of hypertension to guideline targets.

Trial Locations (1)

230032

RECRUITING

Anhui Medical University, Hefei

All Listed Sponsors
lead

Anhui Medical University

OTHER