300
Participants
Start Date
January 1, 2021
Primary Completion Date
December 30, 2024
Study Completion Date
December 30, 2025
Hepatic arterial infusion chemotherapy
Hepatic arterial infusion chemotherapy (HAIC) procedure was performed with FOLFOX regimen: 85 or 135 mg/m2 oxaliplatin from hour 0 to 2 on day 1400 mg/m2 leucovorin from hour 2 to 4 on day 1, and 400 mg/m2 fluorouracil bolus at hour 5 on the day 1; and 2400 mg/m2 fluorouracil over 46 h on days 1 and 2.
Lenvatinib
12 mg (body weight ≥60 kg) , 8 mg (body weight \<60 kg) orally once a day
Tislelizumab
200mg intravenously every 3 weeks
Toripalimab
240mg intravenously every 3 weeks
Sintilimab
200mg intravenously every 3 weeks
Camrelizumab
200mg intravenously every 3 weeks
RECRUITING
Chinese PLA General hospital, Beijing
Sun Yat-sen University
OTHER