NCT06333483View on ClinicalTrials.gov

A Study of CD19 Targeted CAR T Cell Therapy in Patients With Severe, Refractory Systemic Lupus Erythematosus (SLE)

PHASE1RecruitingINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

February 2, 2024

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2026

Conditions
Systemic Lupus Erythematosus
Interventions
BIOLOGICAL

Obecabtagene autoleucel (obe-cel)

Following lymphodepletion with chemotherapy (cyclophosphamide and fludarabine) patients will be treated with a single dose of obe-cel

Trial Locations (3)

08035

RECRUITING

Hospital Universitari Vall Hebrón, Barcelona

NW1 2PG

RECRUITING

University College London Hospitals NHS Foundation Trust, London

M13 9WL

RECRUITING

Manchester Royal Infirmary, Manchester University NHS Foundation Trust,, Manchester

All Listed Sponsors
lead

Autolus Limited

INDUSTRY