396
Participants
Start Date
May 27, 2024
Primary Completion Date
May 31, 2026
Study Completion Date
May 31, 2026
Intrathecal Nicardipine
First, 6 ml of cerebrospinal fluid is withdrawn from the EVD or LD catheter, and then 4 ml (4mg) of nicardipine is injected into the EVD or LD drain tube, followed by 2 ml normal saline solution, and then the EVD or LD tube is clamped for 2 hours, and then kept open as clinically necessary until the next dose (q12h) of medication.
No intervention
"A simulated intrathecal administration operation is performed by a dedicated physician who is unblinded to the group assignment, the EVD or LD tube is not opened, and no drug is given. The simulated administration process needs to be out of the patient's view (if awake patient) and out of the presence of study team personnel."
RECRUITING
Taian Central Hospital, Shandong Province, Tai’an
RECRUITING
Beijing Tiantan Hospital, Affiliated to Capital Medical University, Beijing
RECRUITING
Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai
RECRUITING
The First People's Hospital of Zhenjiang City, Jiangsu Province, Zhenjiang
RECRUITING
Changzhou First People's Hospital, Changzhou
RECRUITING
Affiliated First Hospital of Anhui Medical University, Hefei
RECRUITING
The Second Hospital of Hebei Medical University, Shijiazhuang
RECRUITING
The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou
RECRUITING
Zhejiang Hospital, Hangzhou
RECRUITING
The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou
RECRUITING
Ganzhou People's Hospital, Ganzhou
RECRUITING
Jinggangshan University Affiliated Hospital, Ji’an
RECRUITING
Chongqing Ninth People's Hospital, Chongqing
RECRUITING
Nanyang Central Hospital, Henan Province, Nanyang
RECRUITING
Southern Medical University Zhujiang Hospital, Guangzhou
RECRUITING
Affiliated South China Hospital of Shenzhen University, Shenzhen
RECRUITING
Nanning First People's Hospital, Nanning
RECRUITING
Jinyang Hospital Affiliated to Guizhou Medical University, Guiyang
RECRUITING
Liupanshui City People's Hospital, Liupanshui
RECRUITING
The Second Affiliated Hospital of Guizhou Medical University, Kaili
RECRUITING
Qianfengdong Prefecture People's Hospital, Kaili
RECRUITING
People's Hospital of Qiannan Buyi and Miao Autonomous Prefecture, Guizhou Province, Xingyi
RECRUITING
Qianxinan Prefecture People's Hospital, Xingyi
RECRUITING
Xingyi City People's Hospital, Xingyi
RECRUITING
West China Airport Hospital of Sichuan University, Chengdu
RECRUITING
Western Medical University Affiliated Hospital, Luzhou
RECRUITING
Baotou Central Hospital, Baotou
RECRUITING
The First Hospital of Shanxi Medical University, Taiyuan
The Affiliated Hospital Of Guizhou Medical University
OTHER