Efficacy and Mechanism of FSN Treatment for Senile Knee Osteoarthritis

NANot yet recruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

March 15, 2024

Primary Completion Date

January 1, 2026

Study Completion Date

March 1, 2026

Conditions
Osteoarthritis, Knee
Interventions
DEVICE

Fu's Subcutaneous Needling

Operation of the FSN will follow the KOA's Fu's Subcutaneous Needling Treatment Code of Practice24. After routine disinfection, a disposable Fu's subcutaneous needle ( Nanjing-Paifu Medical Technology Co., Ltd., Jiangsu, China ) is inserted parallel into the subcutaneous loose connective tissue of the pathological tight muscles ( gastrocnemius muscle, tibial anterior muscle and quadriceps femoris muscle ). The FSN needle is operated in a swaying movement. The fan angle is approximately 60°; perform a total of 45 round trips in 30 seconds. Swaying is accompanied by reperfusion approach: 20 sweeps with 10 seconds of reperfusion approach as a group, 3 groups for each pathological tight muscle. The reperfusion approach requires active, short and sharp contractions of the pathological tight muscle. The muscle alternates contraction and relaxation. The FSN group is treated 3 times a week for 2 weeks.

DRUG

Celecoxib

Participants in the drug group will receive celecoxib (capsule) 200mg every day continuously for 2 weeks.

All Listed Sponsors
lead

Guangdong Provincial Hospital of Traditional Chinese Medicine

OTHER

NCT06328153 - Efficacy and Mechanism of FSN Treatment for Senile Knee Osteoarthritis | Biotech Hunter | Biotech Hunter