Dexmedetomidine Infusion Dose Versus Rapid Bolus Dose Before Tracheal Intubation.

PHASE2RecruitingINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

January 21, 2024

Primary Completion Date

April 30, 2024

Study Completion Date

May 31, 2024

Conditions
DexmedetomidineIntubation Complication
Interventions
DRUG

Dexmedetomidine infusion

patients will receive Dexmedetomidine infusion dose of 1 mcg/kg over 10 min before induction.

DRUG

Dexmedetomidine bolus

patients will receive Dexmedetomidine bolus dose of 0.3 mcg/kg over 60 seconds.

DRUG

Atropine Sulfate

If heart rate falls below 45 bpm, rescue dose (500 mcg) of atropine will be given.

DRUG

Ephedrine

If mean blood pressure decreases below 50 mmHg, boluses of 10 mg ephedrine will be given

DRUG

Propofol

Propofol 20 mg boluses till loss of contact

Trial Locations (1)

11562

RECRUITING

Cairo University Hospitals, Giza

All Listed Sponsors
lead

Kasr El Aini Hospital

OTHER