60
Participants
Start Date
September 1, 2024
Primary Completion Date
September 1, 2025
Study Completion Date
June 1, 2027
MRI
The examination lasts between 45 minutes and one hour. The patient lies down in the MRI tube. He is fitted with headphones that muffle the noise produced by the machine and enable him to receive instructions from the technician. Four electrodes are applied to his chest to continuously record his heartbeat. Finally, his chest is covered with a plastic plate, which receives the MRI signals needed to form the image. Acquiring an MRI image takes between 2 and 20 seconds. To ensure that image quality is not impaired by respiratory movements, images are acquired in apnea. The technician will ask the patient to hold his or her breath repeatedly throughout the examination.
Blood sampling
Additional blood will be drawn for dosing acylcarnitines, copeptin, interleukin-6 (IL-6), LPS-Binding Protein (LBP), Phospholipid TransferProtein (PLTP)/Cholesteryl Ester Tranfer Protein (CETP) activity, and for plasma banking. The volume of blood will be 20 ml in total (5 ml for each assay) at each visit. Patients participating in this study will have 3 visits. Total blood volume will therefore be 20 x 3, or 60 ml for the 3 visits.
CHU Dijon - Hopital François Mitterrand, Dijon
CHU Besancon - Hopital Minjoz, Besançon
CHRU Nancy - Hôpital de Brabois, Nancy
CHU Strasbourg - Hopital de HautePierre, Strasbourg
Centre Hospitalier Universitaire de Besancon
OTHER