Clinical Observation of Drug Retention Enema in Preventing Acute Radiation-induced Rectal Injury

NARecruitingINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

June 11, 2024

Primary Completion Date

May 1, 2025

Study Completion Date

December 31, 2025

Conditions
Radiation InjuriesRectal Diseases
Interventions
DRUG

Triethanolamine cream

"Triethanolamine cream retention enema was given once every night before going to bed during radiotherapy until the end of radiotherapy. Triethanolamine cream retention enema was given once before going to bed the day after radiotherapy for 3 months.~Preparation method: Pull out the syringe piston, add 15ml triethanolamine cream, add 30ml normal saline, gently pat, shake well.~Specific methods of retention enema: at night before going to bed, empty urine and feces, prepare enema liquid into the syringe, connect the special catheter, and insert the other end of the special catheter into the anus (the special catheter can be applied with lubricant such as tea oil before insertion). The patient remained prone and semi-seated. Use a special catheter, insert a special catheter about 15cm from the anus, and inject enteral liquid while withdrawing, so that the liquid is retained in the rectum; The above treatment was performed before bed and retained overnight."

Trial Locations (1)

361003

RECRUITING

The First Affiliated Hospital of Xiamen University, Xiamen

All Listed Sponsors
lead

Fujian Cancer Hospital

OTHER_GOV